Cinchocaine 2-丁氧基喹啉-4-羧酸二乙氨基乙酰胺

CAS 85-79-0 MFCD00047595

化学结构图

85-79-0
SMILES: CCCCOc1cc(C(=O)NCCN(CC)CC)c2ccccc2n1

化学属性

Mol. FormulaC20H29N3O2
Mol. Weight343.52

别名和识别编码

Chemical NameCinchocaine
Synonym 2-BUTOXY-N-[2-(DIETHYLAMINO)-ETHYL]-4-QUINOLINE CARBOXAMIDE 2-BUTOXY-N-[2-(DIETHYLAMINO)ETHYL]CINCHONAMIDE 2-Butoxy-N-(2-(diethylamino)ethyl)cinchoninamide 2-Butoxy-N-(beta-diethylaminoethyl)cinchoninamide 2-Butoxy-N-[2-(diethylamino)ethyl]cinchoninamide 2-Butoxyquinoline-4-carboxylic acid diethylaminoethylamide 2-butoxy-n-(2-(diethylamino)ethyl)-4-quinolinecarboxamid 2-butoxy-n-(2-(diethylamino)ethyl)-cinchoninamid 2-butoxy-n-(2-(diethylamino)ethyl)cinchoninamide 2-butoxy-n-(2-(diethylamino)ethyl-4-quinolinecarboxamid 2-butoxy-n-(2-diethylaminoethyl)quinoline-4-carboxamide 2-butoxyquinoline-4-carboxylicaciddiethylaminoethylamide 2-n-butoxy-n-(2-diethylaminoethyl)cinchoninamide 2-丁氧基-N-(2-二乙基氨基乙基)喹啉-4-甲酰胺 4-Quinolinecarboxamide, 2-butoxy-N-(2-(diethylamin
MDL NumberMFCD00047595
PubChem Substance ID3025
EC Number201-632-1
CAS Number85-79-0
Chemical Name Translation2-丁氧基喹啉-4-羧酸二乙氨基乙酰胺
Wiswesser Line NotationT66 BNJ CO4 EVM2N2&2
Beilstein Registry Number0275489
InChIInChI=1S/C20H29N3O2/c1-4-7-14-25-19-15-17(16-10-8-9-11-18(16)22-19)20(24)21-12-13-23(5-2)6-3/h8-11,15H,4-7,12-14H2,1-3H3,(H,21,24)
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分类

  • {uni_hamburg} no charge; nitrogen heterocycle; carbocycle; aromatic; large ring; fused rings; 6ring; 10ring; amide; 1fragment
  • {SA} Alphabetic, Analytical Standards, Analytical/Chromatography, Chemical Structure, Chromatography, D, DIA - DIC, Drugs of Abuse, Forensic and Veterinary Standards, Others

产品应用

  • 强效、长效局部麻醉剂

相关文献及参考

  • Short: EINECS
  • Short: III/31a
  • Merck: 14,3031

安全信息

RTECSGD3150000
GHS Symbol
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P301+P312
  • P305+P351+P338
  • P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
  • P330 Rinse mouth. 漱口
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H318 Causes serious eye damage 严重伤害眼睛
WGK Germany3
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xn
Safety Statements
  • S39 Wear eye/face protection 戴眼睛/面孔保护装置;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
Risk Statements
  • R41 Risk of serious damage to eyes 有严重损伤眼睛的危险
  • R22 Harmful if swallowed 吞咽有害
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 6 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 39,4,1950

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 8500 ug/kg
TOXIC EFFECTS :
   Behavioral - somnolence (general depressed activity)
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - excitement
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 29,368,1932

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 2500 ug/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   PSEBAA Proceedings of the Society for Experimental Biology and Medicine.
   (Academic Press, Inc., 1 E. First St., Duluth, MN 55802)  V.1-    1903/04-
   Volume(issue)/page/year: 29,368,1932

TYPE OF T

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 24500 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)

其他信息

  • Sigma Aldrich:85-79-0(sigmaaldrich)
  • 下游产品:盐酸地布卡因
  • MOL 文件:85-79-0.mol

系列性分类


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