TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 7180 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   WDMBAM Wadley Medical Bulletin.  (Dallas, TX)  V.1-5, 1970-75. For publisher
   information, see JCHODP.  Volume(issue)/page/year: 5,303,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10560 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   WDMBAM Wadley Medical Bulletin.  (Dallas, TX)  V.1-5, 1970-75. For publisher
   information, see JCHODP.  Volume(issue)/page/year: 5,303,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 18800 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceut

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   111,216,1972

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 10310 ug/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   WDMBAM Wadley Medical Bulletin.  (Dallas, TX)  V.1-5, 1970-75. For publisher
   information, see JCHODP.  Volume(issue)/page/year: 5,303,19

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Leukocyte
DOSE/DURATION           : 10 umol/L
REFERENCE :
   EJCODS European Journal of Cancer and Clinical Oncology.  (Pergamon Press,
   c/o Elsevier Science, 660 White Plains Rd., Tarrytown, NY 10591)  V.17(7)-
   25, 1981-89.  For publisher information, see EJCAEL Volume(issue)/page/year:
   17,991,1981

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   GSLNAG Gaslini (Genoa). Rivista de Pediatria e di Specialita Pediatriche.
   (Istituto "Giannina Gaslini," Via Cinque Maggio, 39, 16148 Genoa, Italy)
   V.1-    1969(?)-  Volume(issue)/page/year: 9,10,1977

TYPE OF

TYPE OF TEST            : Cytogenetic analysis
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 500 ug/L
REFERENCE :
   MIKSAM Mikroskopie.  (Verlag Georg Fromme und Co., Spengergasse 39, A 1051
   Vienna 5, Austria) V.1-    1946-  Volume(issue)/page/year:
   29(Suppl),325,1973

TYPE OF TEST            : DNA damage
TEST SYSTEM             : Human Cells - not otherwise specified
DOSE/DURATION           : 10 umol/L
REFERENCE :
   ANTRD4 Anticancer Research.  (5 Argyropoulou St., Kato Patissia, Athens 907,
   Greece)  V.1-    1981-  Volume(issue)/page/year: 11,321,1991

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Fibroblast
DOSE/DURATION           : 25 ug/plate
REFERENCE :
   TUMOAB Tumori.  (Casa Editrice Ambrosiana, Via G. Frua 6, 20146 Milan,
   Italy)  V.1-    1911-  Volume(issue)/page/year: 61,473,1975

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 5 mg/L
REFERENCE :
   EJCAAH European Journal of Cancer.  (