DIETHYLPROPION

CAS 90-84-6 MFCD00056154

化学结构图

90-84-6
SMILES: CCN(CC)C(C)C(=O)c1ccccc1

化学属性

Mol. FormulaC13H19NO
Mol. Weight205.33

别名和识别编码

Chemical NamePropiophenone, 2-diethylamino-
Wiswesser Line Notation2N2&Y1&VR
Synonym Diethylpropione Derfon Magrene Silutin Fenyl-(1-diethylaminoethyl)keton 1-Phenyl-2-diethylamino-1-propanone Diethylpropion Anorex Amphepramone Amfepramone Tepanil 2-(Diethylamino)propiophenone Dobesin Frekentine Danylen Obesitex Tylinal alpha-Benzoyltriethylamine Neobes alpha-Diethylaminopropiophenone Nopropiophenone Adiposon Cegramine UR 1423 1-Propanone, 2-(diethylamino)-1-phenyl-
CAS Number90-84-6
Beilstein Registry Number2804400
PubChem Substance ID7029
InChIInChI=1S/C13H19NO/c1-4-14(5-2)11(3)13(15)12-9-7-6-8-10-12/h6-11H,4-5H2,1-3H3
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安全信息

RTECSUG9450000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >400 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 18,177,1975

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 160 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 20,297,1965

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 24 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JNPHAG Journal de Pharmacologie.  (SPPIF, B.P.22, F-41353 Vineuil, France)
   V.1-    1970-  Volume(issue)/page/year: 17,37,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 11 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - sympathomimetic
   Behavioral - somnolence (general depressed activity)
   Vascular - BP elevation not characterized in autonomic section
REFERENCE :
   THERAP Therapie.  (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris,
   France)  V.1-    1946-  Volume(issue)/page/year: 34,205,1979

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