• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Derivatization Reagents, Derivatization Reagents GC, Reagents for Alkylation & Esterification,
• {SNA} Chromatography Reagents & Solvents, LC-MS Mobile Phase Additives, LC-MS Solvents & Reagents (CHROMASOLV), 分析/色谱, 分析试剂
• {SNA} Analytical Reagents, Analytical/Chromatography, Derivatization Reagents, Derivatization Reagents GC, Reagents for Alkylation & Esterification
• {SNA} Chemical Reagents, Alcohols, Building Blocks, C2 to C6, Chemical Synthesis, Development Quantities for Research, Organic Building Blocks, Oxygen Compounds
• {SNA} Derivatizatio
• {SNA} Analytical Reagents, Analytical/Chromatography, Chromatography Reagents & Solvents, LC-MS Mobile Phase Additives, LC-MS Solvents & Reagents (CHROMASOLV)

产品应用

• Usually used for preparing hexafluoroalcohol-functionalized methacrylate polymers for lithographic/nanopatterning materials.

相关文献及参考

• The esters formed with N-protected amino acids have been investigated as active intermediates in peptide synthesis: J. Org. Chem., 44, 4577 (1979). See Appendix 6.
• Lithiation generates the useful synthon lithium perfluoropropenolate: Org. Synth., 76, 151 (1998):
• The mildly acidic character (pKa 9.3) has been exploited in the selective deprotection of the 4,4'-dimethoxytrityl group in acid-sensitive nucleosides and nucleotides without competing N-gly
• Effective solvent for uncatalyzed epoxidations of alkenes with H2O2 (caution! 60%): Synlett, 248 (2001); or, more conveniently, Urea hydrogen peroxide adduct, L13940: Eur. J. Org. Chem., 3290 (2002). Superior reaction medium for epoxidations, catalyzed by Hexafluoroacetone trihydrate, L10777: Synlett, 1305 (2001). An efficient, selective oxidation of sulfides to sulfoxides with 30% H2O2 employs HFIP as solvent, avoiding over-oxidation to the sulfone: Tetrahedron Lett., 39, 3141 (1998). For a review of fluorinated alcohols as solvents for selective and clean reactions, see: Synlett, 18 (2004).
• Valuable solvent of high polarity and low nucleophilicity: Tetrahedron Lett., 2335 (1974). Extremely powerful H bond donor but poor H bond acceptor: anions are highly solvated, but cations poorly. For feature article on the use of this unique solvent in the stabilization of radical cations, with particular application to EPR spectroscopy, see: Chem. Commun., 2105 (1996). Preferred solvent for the direct substitution of phenol ethers promoted by [Bis(trifluoroacetoxy)­iodo]benzene, L15141: Tetrahedron Lett., 32, 4321 (1991). The intermediacy of radical cations in this reaction has been demonstrated: J. Am. Chem. Soc., 116, 3684 (1994). See also: J. Org. Chem., 60, 7144 (1995).
• Powerful solvent for oligopeptides: Bull. Chem. Soc. Jpn., 61, 281 (1984); 66, 494 (1993). Used alone as a peptide coupling medium, HFIP gives poor results, but as a cosolvent along with proton acceptors such as D

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 300 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 13,1215,1970

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1974 ppm/4H
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Lungs, Thorax, or Respiration - dyspnea
   Blood - other changes
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: OTS0571423

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 600 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JMCMAR Journal of Medicinal Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC
   20037)  V.6-    1963-  Volume(issue)/page/year: 13,1215,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 180 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems
   Laboratory, NIOSH Exchange Chemicals.  (Abe

其他信息

• Sigma Aldrich:920-66-1(sigmaaldrich)
• TCI Shanghai:1,1,1,3,3,3-六氟-2-丙醇 1,1,1,3,3,3-Hexafluoro-2-propanol,>;99.0%(GC)(920-66-1)
• 图谱信息:1,1,1,3,3,3-六氟代-2-丙醇(920-66-1)红外图谱(IR1) 1,1,1,3,3,3-六氟代-2-丙醇(920-66-1)核磁图( 1 HNMR) 1,1,1,3,3,3-六氟代-2-丙醇(920-66-1)质谱(MS)
• Alfa Aesar:1，1，1，3，3，3-六氟代-2-丙醇,99% 1,1,1,3,3,3-Hexafluoro-2-propanol, 99+%(920-66-1)
• 海关编码:29055910
• 下游产品:七氟烷
• TSCA:T
• 上游原料:溴氰
• 六氟异丙醇是一种特种含氟材料，密度高、粘度低、表面张力低。其在紫外光（ <2000A ）下呈透明 , 且折射系数低。可与水或大多数有机溶剂以任意比例互溶，但不溶于长链的烷烃。水中溶解度:1000 g/L (25°C)
• MSDS 信息:1,1,1,3,3,3-Hexafluoro-2-propanol(920-66-1).msds
• Acros Organics:1,1,1,3,3,3-六氟-2-丙醇 1,1,1,3,3,3-Hexafluoro-2-propanol, pure, 99.5+%(920-66-1)
• Hazard Note:Corrosive
• 六氟异丙醇:六氟异丙醇 (简称：HFIP)是一种黏稠的、具有刺激性气味的无色液体。它是溶解聚酰胺和酯类的理想溶剂，可用于分析尼龙。通常情况下，可以在洗脱液中添加少量的三氟醋酸钠以减少样品的聚集。HFIP 虽然有一定的黏度但其沸点很低，通常需要在40 °C条件下进行分析以减少色谱柱的背压。六氟异丙醇还是一种高极性的溶剂，会使混合柱床色谱柱得到的校正曲线变得非线性。因此，安捷伦研发了一种用于该溶剂的特殊的色谱柱—PL HFIPgel 色谱柱，它具有不受溶剂影响的多孔性结构。
• 1,1,1,3,3,3-六氟代-2-丙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 LA1274703 1,1,1,3,3,3-六氟-2-丙醇;1,1,1,3,3,3-六氟异丙醇;六氟异丙醇 100g 1900元 2011/08/23 K5251201 1，1，1，3，3，3-六氟-2-丙醇;1,1,1,3,3,3-六氟异丙醇;六氟异丙醇 25ml 964元 2011/08/23 40080080 1，1，1，3，3，3-；六氟-2-丙醇 25ml 1316元
• 检测方法:GC,NMR
• MOL 文件:920-66-1.mol
• F:27
• 六氟异丙醇价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 LA1274703 1,1,1,3,3,3-六氟-2-丙醇;1,1,1,3,3,3-六氟异丙醇;六氟异丙醇 100g 1900元 2011/08/23 K5251201 1，1，1，3，3，3-六氟-2-丙醇;1,1,1,3,3,3-六氟异丙醇;六氟异丙醇 25ml 964元 2011/08/23 40080080 1，1，1，3，3，3-；六氟-2-丙醇 25ml 1316元
• 用途一:酯化作用试剂,肽和肽中间体的高强溶剂。使用GLC和电子捕获检测测定组织中的芳香酸.也可作为溶剂或清洗剂用于电子行业。其还凭借其可溶解各种聚合物（包括聚酯、聚酰胺、聚丙烯腈、聚缩醛树脂、和水解聚乙烯酯等）的能力而用于大量这些产品的分析中。