DL-Propylhexedrine Hydrochloride

CAS 1007-33-6 MFCD01007336

化学结构图

1007-33-6
SMILES: CC(C)[NH+](C)C1CCCCC1.[Cl-]

化学属性

Mol. Weight191.78
Mol. FormulaC10H21N.ClH

别名和识别编码

CAS Number1007-33-6
Chemical NameCyclohexaneethylamine, N,alpha-dimethyl-,hydrochloride
Synonym Pernsator-wirkstoff 1-Cyclohexyl-2-methylaminopropane hydrochloride Propylhexedrine hydrochloride N,alpha-Dimethylcyclohexaneethylamine hydrochloride Eggobesin Obesin ######## Eventin hydrochloride Benzedrex hydrochloride
Wiswesser Line NotationL6TJ A1Y1&M1 &GH
PubChem Substance ID102541
InChIInChI=1S/C10H21N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h9-11H,3-8H2,1-2H3;1H
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分类

  • Amines
  • Chiral Reagents
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Adrenergic (vasoconstrictor); decongestant (nasal).

相关文献及参考

  • Midha, K.K., et al.: Xenobiotica,?4,?627 (1974),
  • Dutt, M.C., et al.: J. Chromatogr., 248, 115 (1982),

安全信息

RTECSGV1575000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 80 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 100,267,1950

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - man
DOSE/DURATION           : 3571 ug/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP elevation not characterized in autonomic section
   Skin and Appendages - sweating
REFERENCE :
   SMJOAV Southern Medical Journal.  (Southern Medical Assoc., POB 2446,
   Birmingham, AL 35205) V.1-    1908-  Volume(issue)/pa

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 85 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und
   Pharmakologie.  (Berlin, Ger.) V.110-253, 1925-66.  For publisher
   information, see NSAPCC.  Volume(issue)/page/year: 237,171,1959

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 85 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 100,2

系列性分类

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