16?-Hydroxy Progesterone

CAS 438-07-3 MFCD00010484

化学结构图

438-07-3
SMILES: CC(=O)[C@H]1[C@H](O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@@]21C

化学属性

Mol. FormulaC21H30O3
Mol. Weight330.46

别名和识别编码

Chemical Name16?-Hydroxy Progesterone
CAS Number438-07-3
Synonym 16?-Hydroxy-4-pregnene-3,20-dione 16?-Hydroxy-?4-pregnene-3,20-dione 16?-Hydroxyprogesterone (16?)-16-Hydroxypregn-4-ene-3,20-dione NSC 523249 NSC 53910 16α-羟基-4-孕烯-3,20-二酮 16α-羟基孕-4-烯-3,20-二酮 4-孕烯-16α-醇-3,20-二酮
MDL NumberMFCD00010484
Chemical Name Translation
PubChem Substance ID243761
InChIInChI=1S/C21H30O3/c1-12(22)19-18(24)11-17-15-5-4-13-10-14(23)6-8-20(13,2)16(15)7-9-21(17,19)3/h10,15-19,24H,4-9,11H2,1-3H3/t15-,16+,17+,18-,19+,20+,21+/m1/s1
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分类

  • Metabolites & Impurities
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • 16?-Hydroxyprrogesterone is a hydroxylated metabolite of Progesterone (P755900). 16?-Hydroxyprogesterone binds to human progesterone receptors hPR-A and hPR-B and act as an agonist for both receptors.

相关文献及参考

  • Ikonen, M. et al.: Nature, 212, 716 (1966); Storbeck, K.-H. et al.: Mol. Cell. Endocrinol., 336, 92 (2011);

安全信息

WGK Germany3
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter

系列性分类

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