N-Boc-4-(Fmoc-Amino)Piperidine-4-Carboxylic Acid 1-(N-Boc)-4-(N-FMOC-氨基)-4-哌啶甲酸

CAS 183673-66-7 MFCD01318741

化学结构图

183673-66-7
SMILES: CC(C)(C)OC(=O)N1CCC(CC1)(NC(=O)OCC1C2C=CC=CC=2C2C=CC=CC=21)C(O)=O

化学属性

Mol. FormulaC26H30N2O6
Mol. Weight466.53

别名和识别编码

Chemical NameN-Boc-4-(Fmoc-Amino)Piperidine-4-Carboxylic Acid
CAS Number183673-66-7
Synonym 1-(tert-Butoxycarbonyl)-4-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]piperidine-4-carboxylic Ac Fmoc-L-Pip(Boc)-OH, 1-Boc-4-Fmoc-Pip-OH Fmoc-L-Pip(Boc)-OH, 1-Boc-4-Fmoc-Pip-OH N-Boc-4-(Fmoc-氨基)哌啶-4-羧酸
MDL NumberMFCD01318741
PubChem Substance ID57653419
Beilstein Registry Number7609053
Chemical Name Translation1-(N-Boc)-4-(N-FMOC-氨基)-4-哌啶甲酸
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分类

  • Amino Acids & Derivatives
  • Heterocycles
  • {SNA} Chemical Biology, Chemical Synthesis, Others, Peptide Chemistry, Unnatural Amino Acid Derivatives
  • Pharmaceuticals
  • {SNA} Chemical Biology, Chemical Synthesis, Other Unnatural Amino Acids & Derivatives, Peptide Chemistry, Unnatural Amino Acids & Derivatives
  • Intermediates & Fine Chemicals

产品应用

  • N-Boc-amino-(4-N-Fmoc-piperidinyl)carboxylic acid is used in the preparation of synthetic peptide amides as kappa opioid receptor agonists for treatment of pain, pruritis and inflammation associated w

相关文献及参考

  • Ghosh, S., et al.: J. Med. Chem., 49, 2669 (2006),

安全信息

WGK Germany3
GHS Symbol
Precautionary statements
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P305+P351+P338
  • P313 Get medical advice/attention. 获取医疗咨询/就医
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Hazard statements
  • H315 Causes skin irritation 会刺激皮肤
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H335 May cause respiratory irritation 可能导致呼吸道刺激
Signal word Warning
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
  • S37 Wear suitable gloves 戴适当手套；
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置；
Hazard Codes Xi
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性

系列性分类

  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Others - Unnatural Amino Acid Derivatives
  1. Chemical Synthesis 化学合成
  2. Building Blocks 合成砌块
  3. Heterocyclic Building Blocks 杂环合成砌块
  4. Heterocyclic Acids 杂环酸
  5. Piperidine Acids

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