Imidazole-1-ethanol, alpha-(fluoromethyl)-2-nitro-

CAS 13551-89-8 MFCD01319115

化学结构图

13551-89-8
SMILES: [O-][N+](=O)C1=NC=CN1CC(O)CF

化学属性

Mol. FormulaC6H8FN3O3
Mol. Weight189.17

别名和识别编码

Chemical NameImidazole-1-ethanol, alpha-(fluoromethyl)-2-nitro-
Wiswesser Line NotationT5N CNJ A1YQ1F BNW
Synonym 1-(2-Nitro-1-imidazolyl)-3-fluoro-2-propanol SR 1369 NSC 292930 Ro-07-0741 alpha-(Fluoromethyl)-2-nitroimidazole-1-ethanol
CAS Number13551-89-8
Beilstein Registry Number0522249
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安全信息

RTECSNI5566000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 620 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RAREAE Radiation Research.  (Academic Press, Inc., 1 E. First St., Duluth,
   MN 55802)  V.1-    1954-  Volume(issue)/page/year: 91,186,1982

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Unreported
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   USXXAM United States Patent Document.  (U.S. Patent Office, Box 9,
   Washington, DC 20231)  Volume(issue)/page/year: #4371540

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 nmol/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 58,1,1978

TYPE OF TEST            : Morphological transformation
TEST SYSTEM             : Rodent - mouse Embryo
DOSE/DURATION           : 1 mmol/L/3D (Continuous)
REFERENCE :
   45OJAG "Radiation Sensitizers: Their Use in the Clinical Management of
   Cancer, Proceedings of the Conference, Key Biscayne, FL, 1979," Brady, L.W.,
   ed., New York, Masson Pub. USA, Inc., 1980  Volume(issue)/page/year:
   -,146,1980

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