6-Allyl-4-Methoxybenzo[D][1,3]Dioxole 6-烯丙基-4-甲氧基苯并[d][1,3]二氧戊环

CAS 607-91-0 MFCD00133549

化学结构图

607-91-0
SMILES: COC1=CC(CC=C)=CC2OCOC1=2

化学属性

Mol. FormulaC11H12O3
Mol. Weight192.21
Appearance oil

别名和识别编码

Chemical Name6-Allyl-4-Methoxybenzo[D][1,3]Dioxole
CAS Number607-91-0
Synonym myristicinfromparsleyleafoil MYRISTICIN(SG) 6-ALLYL-4-METHOXY-1,3-BENZODIOXOLE 5-Allyl-1-methoxy-2,3-(methylenedioxy) benzene 5-甲氧黃樟油精 肉豆蔻醚 5-Allyl-1-methoxy-2,3-(methylenedioxy)benzene 4-methoxy-6-(2-propenyl)-3-benzodioxole 6-allyl-4-methoxy-1,3-benzodioxole Myristicine MYRISTICIN WITH GC 肉豆蔻醚 来源于欧芹叶油 4-METHOXY-6-[2-PROPENYL]-1,3-BENZODIOXOLE 1,3-Benzodioxole, 4-methoxy-6-(2-propenyl)- 4-Methoxy-6-(2-propenyl)-1,3-benzodioxole 5-烯丙基-2,3-(亚甲二氧基)苯甲醚 6-烯丙基-4-甲氧基-1,3-苯并二茂 Myristicin 5-allyl-1-methoxy-2,3-(methylenedioxy)-benzen 5-methoxysafrole 4-Methoxy-6-allyl-1,3-benzodioxole 6-Allyl-4-methoxy-1,3-benzodioxole MYRISTICIN MYRISTICIN FROM PARSLEY OIL 7-Methoxy-5-(2-propenyl)-1,3-benzodioxole 5-Allyl-2,3-(methylendioxy)anisole, 6-Allyl-4-methoxy-1,3-benzodioxole 6-allyl-4-methoxy-benzo-1,3-dioxole 肉豆蔻精 5-ALLYL-2,3-(METHYLENDIOXY)ANISOLE 5-烯丙基-2,3-(亚甲二氧基)苯甲醚 5-Allyl-2,3-(methylendioxy)anisole; 6-Allyl-4-methoxy-1,3-benzodioxole Benzene, 5-allyl-1-methoxy-2,3-(methylenedioxy)-
MDL NumberMFCD00133549
PubChem Substance ID24897334
EC Number210-146-9
Beilstein Registry Number0166218
Chemical Name Translation6-烯丙基-4-甲氧基苯并[d][1,3]二氧戊环
Wiswesser Line NotationT56 BO DO CHJ FO1 H2U1
LabNetwork Molecule IDLN01306062
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分类

  • {SNA} Alphabetica
  • Heterocycles
  • {SNA} Bioactive Small Molecule Alphabetical Index, M, 一氧化氮和细胞应激, 氧化应激蛋白和试剂,
  • {SNA} Analytical Standards, Analytical/Chromatography, Cell Biology, Chemical Class, Chromatography, Ephedra sinica, Life Sciences Standards, Myristica, Natural Compounds, Natural Terpene Standards, Nutrition Research, Phytochemicals by Plant (Food/Spice/Herb), Phytopharma Standards, Standards by Plant Genus
  • {SNA} Cell Stress, M, Nitric Oxide and Cell Stress, Oxidative Stress Proteins and Reagents, 生物活性小分子, 细胞信号转导和神经科学,

产品应用

  • A naturally occurring insecticide and acaricide with possible neurotoxic effects on neuroblastoma cells.

相关文献及参考

  • [2]. Dawidowicz AL, et al. Simple and rapid determination of myristicin in human serum.Forensic Toxicol. 2013 Jan;31(1):119-123. Epub 2012 Aug 15.
  • Lee, B.K. et al.: Toxicol. Lett., 157, 49 (2005); Srivastava, S. et al.: Pharmac. Biol., 39, 226 (2001);
  • Short: III/35C3 Title: Nuclear Magnetic Resonance (NMR) Data: Chemical Shifts and Coupling Constants for Hydrogen-1, Part 3: Natural Compounds Author: Gupta, R.R.; Dobhal, M.P. Editor: Gupta, R.R.; Lechner, M.D. Source: Landolt-Börnstein, New Series Volume: III/35C3 Year: 2003 Keyword: chemical shift; coupling constant; molecular structure ISBN: 3-540-41058-9 ISBN: 978-3-540-41058-4 Internet Resource: DOI:10.1007/b76569 RefComment: VIII, 322 pages. With CD-ROM. Hardcover Abstract: This volume provides a comprehensive and evaluated compilation of nuclear magnetic resonance data. Chemical shifts and coupling constants of boron-11 and phosphorus-31 (subvol. A), fluorine-19 and nitrogen-15 (subvol. B), hydrogen-1

安全信息

GHS Symbol
Precautionary statements
  • P308+P313
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
Hazard statements
  • H361 Suspected of damaging fertility or the unborn child 怀疑对生育能力或未出生婴儿造成伤害
  • H412 Harmfutoaquaticlifewithlonglastingeffects 对水生生物有害并具有长期影响。
WGK Germany3
Signal word Warning
RTECSCY2625000
Personal Protective Equipment Eyeshields, Gloves Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
Risk Statements
  • R52/53
UN Number 3082 UN 3082 9/PG 3
Storage condition 2-8°C 储存温度2-8°C
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 900 mg/kg
TOXIC EFFECTS :
   Brain and Coverings - recordings from specific areas of CNS
   Liver - other changes
   Nutritional and Gross Metabolic - body temperature decrease
REFERENCE :
   AMJPA6 American Journal of Pharmacy (1835-1936).  (Philadelphia, PA)
   V.1-108, 1835-1936.  Volume(issue)/page/year: 80,563,1909

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4260 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JAFCAU Journal of Agricultural and Food Chemistry.  (American Chemical Soc.,
   Distribution Office Dept. 223, POB 57136, West End Stn., Washington, DC
   20037)  V.1-    1953-  Volume(issue)/page/year: 30,563,1982

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 5700 ug/kg
TOXIC EFFECTS :
   Behavioral - wakefulness
   Behavioral - euphoria
   Behavioral - hallucinations, distorted perceptions
REFERENCE :
   JNEUAY Journal of Neuropsychiatry.  (Chicago, IL)  V.1-5, 1959-64.  For
   publisher information, see BENPBG.  Volume(issue)/page/year: 2,205,1961

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 400 mg/kg
TOXIC EFFECTS :
   Behavioral - general anesthetic
   Liver - fatty liver degeneration
REFERENCE :
   AMJPA6 American Journal of Pharmacy (1835-1936).  (Philadelphia, PA)
   V.1-108, 1835-1936.  Volume(issue)/page/year: 80,563,1909

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF

TYPE OF TEST            : DNA adduct
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 400 mg/kg
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 5,1613,1984

其他信息

  • 储运特性:库房通风低温干燥; 与食品原料分开储运
  • 类别:农药
  • 毒性分级:中毒
  • color:clear, light yellow
  • Sigma Aldrich:607-91-0(sigmaaldrich)
  • F:10-23
  • 急性毒性:口服- 大鼠 LD50: 4620 毫克/ 公斤
  • 灭火剂:干粉、泡沫、砂土
  • MOL 文件:607-91-0.mol

系列性分类


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