1-((2R,4R,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione 1-((2R,4R,5R)-4-羟基-5-((三苯甲基氧基)甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮

CAS 55612-11-8 MFCD00134202

化学结构图

55612-11-8
SMILES: CC1=CN([C@H]2C[C@@H](O)[C@@H](COC(C3C=CC=CC=3)(C3C=CC=CC=3)C3C=CC=CC=3)O2)C(=O)NC1=O

化学属性

Mol. FormulaC29H28N2O5
Mol. Weight484.54
Melting Point246-248 °C (lit.)

别名和识别编码

Chemical Name1-((2R,4R,5R)-4-Hydroxy-5-((trityloxy)methyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione
CAS Number55612-11-8
Synonym 5′-O-三苯代甲基-2′-脱氧-β-D-呋喃来苏糖基胸苷 5′-O-三苯代甲基-2′-脱氧-β-D-呋喃来苏糖基胸苷 1-[2-Deoxy-5-O-(triphenylmethyl)-?-D-threo-pentofuranosyl]-5-methyl-
MDL NumberMFCD00134202
PubChem Substance ID24862245
EC Number407-120-6
Chemical Name Translation1-((2R,4R,5R)-4-羟基-5-((三苯甲基氧基)甲基)四氢呋喃-2-基)-5-甲基嘧啶-2,4(1H,3H)-二酮
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分类

  • Bases & Related Reagents
  • Nucleotides
  • {SNA} Carbohydrate Chemistry, Carbohydrate Derivatives, Chemical Biology, Chemical Synthesis
  • Heterocycles
  • Intermediates
  • Aromatics

产品应用

  • An intermediate in the preparation of thymidine monophosphate analogues

相关文献及参考

  • Vanheusden, V., et al.: Bioorg. Med. Chem. Lett., 12, 2695 (2002),

安全信息

WGK Germany1
Hazard statements
  • H413 Maycauselonglastingharmfuleffectstoaquaticlife 可能对水生生物造成长期持续有害影响。
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Gloves
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中，参考特别指示/安全收据说明书；
Risk Statements
  • R53 May cause long-term adverse effects in the aquatic environment 对水生环境有长期的有害作用

系列性分类

  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Carbohydrate Chemistry - Chemical Biology
  4. Carbohydrate Derivatives 碳水化合物衍生物

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