(2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl dihydrogen phosphate (2R,3r,4s,5r)-2,3,4,5-四羟基-6-氧代己基膦酸二氢盐
CAS 56-73-5 MFCD00136040
化学结构图
SMILES:
化学属性
| Mol. Formula | C6H13O9P |
|---|---|
| Mol. Weight | 260.14 |
| Density | 1.97 |
别名和识别编码
| Chemical Name | (2R,3R,4S,5R)-2,3,4,5-tetrahydroxy-6-oxohexyl dihydrogen phosphate |
|---|---|
| Synonym | D-Glucose 6-phosphate {LY} D-Glucose 6-phosphate D-Glucose 6-phosphate solution D-葡糖-6-磷酸 D-葡萄糖-6-磷酸 Glucose-6-phosphate L-2-氨基-3,3-二甲基丁酸-6-磷酸 {} {LY} D-Glucose 6-phosphate {} {} {LY} D-Glucose 6-phosphate {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-Glucose 6-phosphate {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} D-G |
| CAS Number | 56-73-5 |
| EC Number | 200-286-9 |
| Beilstein Registry Number | 2384789 |
| MDL Number | MFCD00136040 |
| PubChem Substance ID | 24895321 |
| Chemical Name Translation | (2R,3r,4s,5r)-2,3,4,5-四羟基-6-氧代己基膦酸二氢盐 |
| LabNetwork Molecule ID | LN01363764 |
| Canonical SMILES | O=C[C@@H]([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)O |
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分类
- {SNA} Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates G, Monosaccharide
产品应用
- D-葡萄糖-6-磷酸结合并抑制大鼠脑组织心肌细胞肌浆网钙ATP酶(sarcoendoplasmic reticulum calcium ATPase)的活性, 导致内质网中的钙积累的减少
相关文献及参考
- Merck: 14,4462
- [1]. Olsen BB, et al. Linked Hexokinase and Glucose-6-Phosphatase Activities Reflect Grade of Ovarian Malignancy. Mol Imaging Biol. 2018 Jul 9.
安全信息
GHS Symbol
- S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时，立即求医（可能时出示标签）；
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S27 Take off immediately all contaminated clothing 立即脱掉全部污染的衣服；
- S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R34 Causes burns 会导致灼伤
- P310 Immediately call a POISON CENTER or doctor/physician. 立即呼救解毒中心或医生/医师。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P305+P351+P338
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
- H314 Causes severe skin burns and eye damage 导致严重的皮肤灼伤和眼睛损伤
TYPE OF TEST : DNA damage TEST SYSTEM : Microorganism - not otherwise specified DOSE/DURATION : 10 mmol/L REFERENCE : PNASA6 Proceedings of the National Academy of Sciences of the United States of America. (National Academy of Sciences, Printing & Pub. Office, 2101 Constitution Ave., Washington, DC 20418) V.1- 1915- Volume(issue)/page/year: 81,105,1984
其他信息
- D-Glucose 6-phosphate solution is a sarcoendoplasmic reticulum calcium ATPase activity inhibitor that decreases the amount of calcium present in the endoplasmic reticulum (ER).
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