Permethrin 氯菊酯

CAS 52645-53-1 MFCD00041809

化学结构图

52645-53-1
SMILES: CC1(C)[C@@H]([C@@H]1C=C(Cl)Cl)C(=O)OCc1cccc(c1)Oc1ccccc1

化学属性

Mol. FormulaC21H20Cl2O3
Mol. Weight391.31
Density1.19
Refractive index1.5627
SolubilitySoluble in water (Partly miscible), DMSO (40 mg/ml), and ethanol (25 mg/ml).
Boiling Point198-200°C
Melting Point35°C

别名和识别编码

Chemical NamePermethrin
MDL NumberMFCD00041809
PubChem Substance ID24869115
Beilstein Registry Number2063148
CAS Number52645-53-1
EC Number258-067-9
Synonym Exmin Coopex Ambush AI3-29158 Kestrel MP79 Efmethrin FMC 41655 Ambushfog Permasect-25EC Peregin Exsmin LE 79-519 Anomethrin N Antiborer 3768 ICI-PP 557 Diffusil H Permetrin FMC 33297 Peregin W Outflank-stockade Outflank NRDC 143 氯菊脂 Kafil Ectiban 氯菊脂(异构体) 溶液 Permethrin Ipitox Chinetrin OMS 1821 Permitrene Indothrin Ecsumin Permetrina Dragnet BW-21-Z NIA 33297 Corsair Permasect 3-Phenoxybenzyl
Chemical Name Translation氯菊酯
InChIKeyRLLPVAHGXHCWKJ-HKUYNNGSSA-N
Wiswesser Line NotationL3TJ A1 A1 B1UYGG CVO1R COR
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

分类

  • {SNA} mixture of cis and trans isomers
  • {SA} Acaricides, Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, EPA, Endocrine Disruptors (Draft), Environmental Standards,
  • Acaricides, Alpha sort, Alphabetic, Analytical Standards, Analytical/Chromatography, Chromatography, EPA, Endocrine Disruptors (Draft), Environmental Standards, Insecticides, Method Specific, N-P, P, PER - POLA, Pesticides, Pesticides & Metabolites, Pyrethroids
  • {SNA} Acaricides

产品应用

  • A pyrethroid sodium channel modifier

相关文献及参考

  • Merck 14 ,7180

安全信息

RTECSGZ1255000
GHS Symbol
Precautionary statements
  • P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking. 远离热源/火花/明火/热的表面。——禁止吸烟。
  • P273 Avoid release to the environment. 避免释放到环境中。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P305+P351+P338
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
  • P304+P340+P312
  • P333+P313
Hazard statements
  • H332 Harmful if inhaled 吸入有害
  • H302 Harmful if swallowed 吞食有害
  • H312 Harmful in contact with skin 皮肤接触有害
  • H411 Toxictoaquaticlifewithlonglastingeffects 对水生生物有毒性并具有长期影响。
  • H319 Causes serious eye irritation 严重刺激眼睛
  • H225 Highly flammable liquid and vapour 高度易燃液体和蒸气
  • H410 Verytoxictoaquaticlifewithlonglastingeffects 对水生生物毒性非常大并具有长期影响。
  • H317 May cause an allergic skin reaction 可能导致皮肤过敏
Hazard Codes F,T,N F,Xn,N Xn,N
WGK Germany3
Personal Protective Equipment Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Signal word Danger Warning
Safety Statements
  • S61 Avoid release to the environment. Refer to special instructions/safety data sheet 避免释放到环境中,参考特别指示/安全收据说明书;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套;
  • S16 Keep away from sources of ignition - No smoking 远离火源,禁止吸烟;
  • S24 Avoid contact with skin 避免皮肤接触;
  • S60 This material and its container must be disposed of as hazardous waste 该物质及其容器必须作为危险废物处置;
  • S13 Keep away from food, drink and animal foodstuffs 远离食品、饮料和动物饲料保存;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
Risk Statements
  • R11 Highly flammable 非常易燃
  • R51/53
  • R20/21/22 Harmful by inhalation, in contact with skin and if swallowed 吸入、皮肤接触和不慎吞咽有害
  • R36 Irritating to eyes 刺激眼睛
  • R20/22 Harmful by inhalation and if swallowed 吸入和不慎吞咽有害
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
  • R50/53
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - quail
DOSE/DURATION           : 13500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de
   Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France)
   V.1-  1947-  Volume(issue)/page/year: 32,168,1978

TYPE OF TEST            : LD50 - Let

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Bird - domestic
DOSE/DURATION           : 32 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de
   Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France)
   V.1-  1947-  Volume(issue)/page/year: 32,168,1978

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 383 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD-A047-284

TYPE OF TEST            : LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE       : Inhalation
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 485 mg/m3
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   GISAAA Gigiena i Sanitariya.  For English translation, see HYSAAV.  (V/O
   Mezhdunarodnaya Kniga, 113095 Moscow, USSR)  V.1-    1936-
   Volume(issue)/page/year: 55(12),21,1990

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Rodent - mouse Leukocyte
DOSE/DURATION           : 110 umol/L
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 140 umol/L
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 10,291,1987

TYPE OF TEST            : Micronucleus test
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 10 mg/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   20,218,1992

TYPE OF

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 139 ug/kg
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
REFERENCE :
   PHABDI Proceedings of the Hungarian Annual Meeting for Biochemistry. (Magyar
   Kemikusok Egyesulete, Anker Koz 1, 1061 Budapest, Hungary)  V.1- 1961- 
   Volume(issue)/page/year: 21,227,1981

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 139 ug/kg
REFERENCE :
   DCTODJ Drug and Chemical Toxicology.  (Marcel Dekker, 270 Madison Ave., New
   York, NY 10016) V.1-    1977/78-  Volume(issue)/page/year: 10,291,1987

TYPE OF TEST            : DNA inh

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 250 mg/kg
SEX/DURATION            : female 6-15 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   BECTA6 Bulletin of Environmental Contamination and Toxicology.
   (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ
   07094)  V.1-    1966-  Volume(issue)/page/year: 29,84,1982

其他信息

  • Permethrin is a widely-used pesticide of the pyrethroid family. Permethrin interacts with voltage-gated Na+ channels and inhibits their natural deactivation, causing the channels to remain open for a long time and destroying equilibrium of the neuronal system. Pyrethroids are also thought to interact with GABA receptors and associated pathways.

系列性分类


相关产品推荐