安全信息
RTECS | OL5975000 |
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Vascular - relaxation (isolated tissues)
Lungs, Thorax, or Respiration - other changes
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
REFERENCE :
WILEAR Wiadomosci Lekarskie. Medical News. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.1- 1948- Volume(issue)/page/year: 27,1211,1974
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 5 gm/kg
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
acute tubular necrosis)
Kidney, Ureter, Bladder - urine volume decreased
Nutritional and Gross Metabolic - metabolic acidosis
REFERENCE :
WILEAR Wiadomosci Lekarskie. Medical News. (Ars Polona, POB 1001, 00-068
Warsaw 1, Poland) V.1- 1948- Volume(issue)/page/year: 27,1211,1974
TYPE OF TEST : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE : Oral
SPECIES OBSERVED : Human - woman
DOSE/DURATION : 2 gm/kg
TOXIC EFFECTS :
Behavioral - general anesthetic
Behavioral - coma
Gastrointestinal - other changes
REFERENCE :
BEGMA5 Beitraege zur Gerichtlichen Medizin. (Verlag Franz Deuticke,
Helferstorferstr 4, A-1010 Vienna, Austria) V.1- 1911-
Volume(issue)/page/year: 13,56,1935