Sodium Propylparaben 尼泊金丙酯钠
CAS 35285-69-9 MFCD00016477
化学结构图
SMILES: [Na+].CCCOC(=O)C1C=CC([O-])=CC=1
化学属性
| Mol. Formula | C10H11NaO3 |
|---|---|
| Mol. Weight | 202 |
别名和识别编码
| Chemical Name | Sodium Propylparaben |
|---|---|
| Synonym | 4-羟基苯甲酸丙酯钠盐 尼泊金丙酯钠 对羟基苯甲酸丙酯 钠盐 Propyl-p-hydroxybenzoate, sodium salt |
| MDL Number | MFCD00016477 |
| PubChem Substance ID | 24890084 |
| Beilstein Registry Number | 5183350 |
| EC Number | 252-488-1 |
| Chemical Name Translation | 尼泊金丙酯钠 |
| Wiswesser Line Notation | OR DVO3 &-NA- |
| CAS Number | 35285-69-9 |
信息真实价格透明
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信息真实价格透明
资金保障
专业采购外包团队在线服务
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现货库存
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分类
- {SNA} Pharmacopoeia, Pharmacopoeia A-Z, 分析/色谱
- {SA} Pharmacopoeia, Pharmacopoeia A-Z
相关文献及参考
- [2]. Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic products. Int J Toxicol. 2008;27 Suppl 4:1-82.
- [3]. S Oishi, et al. Effects of propyl paraben on the male reproductive system. Food Chem Toxicol. 2002 Dec;40(12):1807-13.
- [1]. Gal A, et, al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106.
- [1]. Gal A, et, al. Propylparaben inhibits mouse cultured antral follicle growth, alters steroidogenesis, and upregulates levels of cell-cycle and apoptosis regulators. Reprod Toxicol. 2019 Oct;89:100-106.
- [2]. Final amended report on the safety assessment of Methylparaben, Ethylparaben, Propylparaben, Isopropylparaben, Butylparaben, Isobutylparaben, and Benzylparaben as used in cosmetic prod
安全信息
TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 85 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRSTAT Drug Standards. (Washington, DC) V.19-28, 1951-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 20,89,1952
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 490 mg/kg TOXIC EFFECTS : Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - somnolence (general depressed activity) Behavioral - changes in motor activity (specific assay) REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49, 1940-60. For publisher information, see JPMSAE. Volume(issue)/page/year: 45,260,1956
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 180 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JAPMA8 Journal of the American Pharmaceutical Association, Scientific Edition. (Washington, DC) V.29-49,
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