2H-Benzimidazol-2-one,1,3-dihydro-1-(3-((2-hydroxy-3-(1-naphthalenyloxy)propyl)amino)-3- methylbutyl)-, monohydrochloride,monohydrate

CAS 75708-29-1 MFCD01658791

化学结构图

75708-29-1
SMILES: O.Cl.CC(C)(CCN1C(=O)NC2C=CC=CC1=2)NCC(O)COC1C=CC=C2C=CC=CC2=1

化学属性

Mol. FormulaC25H29N3O3.ClH.H2O
Mol. Weight474.05

别名和识别编码

Chemical Name2H-Benzimidazol-2-one,1,3-dihydro-1-(3-((2-hydroxy-3-(1-naphthalenyloxy)propyl)amino)-3- methylbutyl)-, monohydrochloride,monohydrate
Synonym Adimolol hydrochloride hydrate MEN-935
CAS Number75708-29-1
Chemical Name Translation
信息真实价格透明    资金保障    专业采购外包团队在线服务   
信息真实价格透明    资金保障    专业采购外包团队在线服务   
品牌质保精细包装    现货库存    一流品牌服务   

安全信息

RTECSDE2276200 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >590 mg/kg
TOXIC EFFECTS :
   Details of to

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year: 11,9,1986

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human
DOSE/DURATION           : 10700 ug/kg/25D-I
TOXIC EFFECTS :
   Cardiac - pulse rate
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 35,964,1985

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 11800 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year: 11,9,1986

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 16400 ug/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   DRFUD4 Drugs of the Future.  (J.R. Prous, S.A., Apartado de Correos 540,
   08080 Barcelona, Spain) V.1-    1975/76-  Volume(issue)/page/year: 11,9,1986

系列性分类

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