6H-Benzo(d)naphtho(1,2-b)pyran-6-one,4-(6-deoxy-alpha-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-

CAS 77879-89-1 MFCD01662195

化学结构图

77879-89-1
SMILES: CC1C=C(OC)C2=C(C=1)C(=O)OC1C3=C(C(O)=CC=C3[C@H]3O[C@H]([C@@H](O)[C@H]3O)[C@@H](C)O)C(=CC=12)OC

化学属性

Mol. FormulaC26H26O9
Mol. Weight482.52

别名和识别编码

Chemical Name6H-Benzo(d)naphtho(1,2-b)pyran-6-one,4-(6-deoxy-alpha-galactofuranosyl)-1-hydroxy-10,12-dimethoxy-8-methyl-
Wiswesser Line NotationT E6 B666 COVJ G1 IO1 MO1 OQ R- BT5OTJ CQ DQ EYQ1
Synonym DC-38-M Gilvocarcin M
Beilstein Registry Number5675008
CAS Number77879-89-1
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安全信息

RTECSDI2250000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JKXXAF Japanese Kokai Tokyo Koho Patents.  (U.S. Patent and Trademark
   Office, Foreign Patents, Washington, DC 20231)  Volume(issue)/page/year:
   #81-22781

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 450 mg/kg
TOXIC EFFECTS :
   Tumorigenic - active as anti-cancer agent
REFERENCE :
   JANTAJ Journal of Antibiotics.  (Japan Antibiotics Research Assoc., 2-20-8
   Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan)  V.2-5, 1948-52;  V.21- 1968-
   Volume(issue)/page/year: 34,701,1981

系列性分类

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