Acetohydroxamic acid,N-(fluoren-2-yl)-O-tetradecanoyl-

CAS 63224-44-2 MFCD01673025

化学结构图

63224-44-2
SMILES: CC(=O)N(OC(=O)CCCCCCCCCCCCC)C1=CC2CC3C=CC=CC=3C=2C=C1

化学属性

Mol. FormulaC29H39NO3
Mol. Weight449.69

别名和识别编码

Chemical NameAcetohydroxamic acid,N-(fluoren-2-yl)-O-tetradecanoyl-
Wiswesser Line NotationL B656 HHJ ENV1&OV13
Synonym N-Myristoyloxy-aaf N-Myristoyloxy-N-acetyl-2-aminofluorene N-(Fluoren-2-yl)-o-tetradecanoylacetohydroxamic acid N-Acetyl-N-myristoyloxy-2-aminofluorene N-Acetyl-N-tetradecanoyloxy-2-aminofluorene
CAS Number63224-44-2
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安全信息

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 115 mg/kg/6W-I
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 2,655,1981

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 114 mg/kg/5W-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Tumorigenic - tumors at site of application
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   37,1461,1977

RTECSAL0300000 
TYPE OF TEST            : Mutation in mammalian somatic cells
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 50 umol/L/3H
REFERENCE :
   CALEDQ Cancer Letters (Shannon, Ireland).  (Elsevier Scientific Pub. Ireland
   Ltd., POB 85, Limerick, Ireland)  V.1-    1975- Volume(issue)/page/year:
   6,67,1979

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Human Fibroblast
DOSE/DURATION           : 10 umol/L/5H
REFERENCE :
   IJCNAW International Journal of Cancer.  (International Union Against
   Cancer, 3 rue du Conseil- General, 1205 Geneva, Switzerland)  V.1-    1966-
   Volume(issue)/page/year: 16,284,1975

系列性分类

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