1-alpha-H,5-alpha-H-Tropan-3-alpha-ol,3'-(trifluoromethyl)phenyl ether, hydrochloride

CAS 20382-89-2 MFCD01677337

化学结构图

20382-89-2
SMILES: Cl.CN1[C@@H]2C[C@H](C[C@H]1CC2)OC1C=C(C=CC=1)C(F)(F)F |&1:3,5,7|

化学属性

Mol. FormulaC15H18F3NO.ClH
Mol. Weight321.80

别名和识别编码

Chemical Name1-alpha-H,5-alpha-H-Tropan-3-alpha-ol,3'-(trifluoromethyl)phenyl ether, hydrochloride
Wiswesser Line NotationT56 A ANTJ A1 GOR CXFFF &GH
Synonym N-1149 hydrochloride Tropine-3-beta-(3'-trifluoromethylphenyl) ether hydrochloride
CAS Number20382-89-2
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安全信息

RTECSYM6050000
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 261 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 72 mg/kg
TOXIC EFFECTS :
   Autonomic Nervous System - parasympatholytic
   Behavioral - excitement
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 45 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
   Autonomic Nervous System - parasympatholytic
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 18,517,1968

系列性分类


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