Quinazoline,4-(2,3-dihydroxypropylamino)-2-(5-nitro-2-thienyl)-

CAS 33372-40-6 MFCD01686616

化学结构图

33372-40-6
SMILES: [O-][N+](=O)C1=CC=C(S1)C1N=C(NCC(O)CO)C2C=CC=CC=2N=1

化学属性

Mol. FormulaC15H14N4O4S
Mol. Weight346.39

别名和识别编码

Chemical NameQuinazoline,4-(2,3-dihydroxypropylamino)-2-(5-nitro-2-thienyl)-
Wiswesser Line NotationT66 BN DNJ EM1YQ1Q C- BT5SJ ENW
Synonym 4-(2,3-Dihydroxypropylamino)-2-(5-nitro-2-thienyl)quinazoline 1,2-Propanediol, 3-((2-(5-nitro-2-thienyl)-4-quinazolinyl)amino)- PNTQ
Beilstein Registry Number0580977
CAS Number33372-40-6
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安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8313 mg/kg/47W-C
TOXIC EFFECTS :
   Tumorigenic - Carcinogenic by RTECS criteria
   Gastrointestinal - tumors
   Skin and Appendages - tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.  Volume(issue)/page/year:
   57,277,1976

RTECSVA1375000
TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 ug/plate
REFERENCE :
   CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut
   Sts., Philadelphia, PA 19106)  V.1-    1941-  Volume(issue)/page/year:
   35,3611,1975

系列性分类


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