5-Phenylpyridin-2-amine 2-氨基-5-苯基吡啶
CAS 33421-40-8 MFCD01692452
化学结构图
SMILES: Nc1ccc(-c2ccccc2)cn1
化学属性
| Mol. Formula | C11H10N2 |
|---|---|
| Mol. Weight | 170 |
| Melting Point | 134-138 |
| TSCA | No |
别名和识别编码
| Chemical Name | 5-Phenylpyridin-2-amine |
|---|---|
| CAS Number | 33421-40-8 |
| Alfabeta Name | AMINOPHENYLPYRIDINE 25--- |
| MDL Number | MFCD01692452 |
| Synonym | 2-Amino-5-phenylpyridine 5-Phenyl-2-pyridinamine 5-Phenylpyridin-2-ylamine Phe-P-1 |
| Reaxys-RN | 120219 |
| PubChem Substance ID | 87563086 |
| Chemical Name Translation | 2-氨基-5-苯基吡啶 |
| Wiswesser Line Notation | T6NJ BZ FR |
| Beilstein Registry Number | 120219 |
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信息真实价格透明
资金保障
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分类
- Building Blocks, C11, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
产品应用
- A product from the pyrolysis of phenylalanine.
相关文献及参考
- [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9.
- Kim, D., et al.: Bioorg. Med. Chem. Lett., 15, 2129 (2005),
- [1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103.
- [1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103.
- [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9.
安全信息
- H315 Causes skin irritation 会刺激皮肤
- H319 Causes serious eye irritation 严重刺激眼睛
- H301 Toxic if swallowed 吞食有毒
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P305+P351+P338
- P305+P351+P338+P337+P313
- P332+P313
- P362 Take off contaminated clothing and wash before reuse. 脱掉污染的衣服，清洗后方可重新使用
- S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后，立即用大量水冲洗并征求医生意见；
- S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
- R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
- R40 Limited evidence of a carcinogenic effect 有限证据表明其致癌作用
GHS Symbol
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 100 ug/plate REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 26,611,1978
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