Pyridazine,3-hydrazino-6-((2-hydroxypropyl)methylamino)-,dihydrochloride

CAS 56393-22-7 MFCD01692830

化学结构图

56393-22-7
SMILES: Cl.Cl.CC(O)CN(C)C1C=CC(NN)=NN=1

化学属性

Mol. FormulaC8H15N5O.2ClH
Mol. Weight270.20

别名和识别编码

Chemical NamePyridazine,3-hydrazino-6-((2-hydroxypropyl)methylamino)-,dihydrochloride
Wiswesser Line NotationT6NNJ CMZ F1M1YQ1 &GH 2
Synonym Atensil 3-Hydrazino-6-((2-hydroxypropyl)methylamino)pyridazine dihydrochloride 6-((2-Hydroxypropyl)methylamino)-3(2H)-pyridazinone hydrazone
CAS Number56393-22-7
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安全信息

RTECSUR6040000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 355 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   8,295,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1230 mg/kg
TOXIC EFFECTS :
   Cardiac - pulse rate increase, without fall in BP
   Vascular - BP lowering not characterized in autonomic section
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   8,295,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 357 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   8,295,1976

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1170 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PLRCAT Pharmacological Research Communications.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802)  V.1-    1969-  Volume(issue)/page/year:
   8,295,1976

系列性分类

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