Platinum, dimethylbis(sulfinylbis(methane)-S)-,(SP-4-2)-

CAS 70423-98-2 MFCD01699108

化学结构图

70423-98-2
SMILES: C[Pt]C.CS(C)=O.CS(C)=O

化学属性

Mol. FormulaC6H18O2PtS2
Mol. Weight381.45

别名和识别编码

Chemical NamePlatinum, dimethylbis(sulfinylbis(methane)-S)-,(SP-4-2)-
Synonym cis-Dimethylbis(sulfinylbis(methane)-S)platinum Dimethylbis(sulfinylbis(methane)-S)platinum (SP-4-2)
CAS Number70423-98-2
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安全信息

RTECSTP2497600 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 46400 ug/kg
TOXIC EFFECTS :
   Liver - other changes
REFERENCE :
   ANTDEV Anti-Cancer Drugs.  (Rapid Communications of Oxford Ltd., The Old
   Malthous, Paradise St., Oxford OX1 1LD, UK)  V.1-    1990-
   Volume(issue)/page/year: 3,9,1992

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 100 mg/kg
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, other (after systemic exposure)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   ANTDEV Anti-Cancer Drugs.  (Rapid Communications of Oxford Ltd., The Old
   Malthous, Paradise St., Oxford OX1 1LD, UK)  V.1-    1990-
   Volume(issue)/page/year: 3,9,1992

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 51200 ug/kg
TOXIC EFFECTS :
   Kidney, Ureter, Bladder - changes in tubules (including acute renal failure,
   acute tubular necrosis)
   Blood - other changes
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   ANTDEV Anti-Cancer Drugs.  (Rapid Communications of Oxford Ltd., The Old
   Malthous, Paradise St., Oxford OX1 1LD, UK)  V.1-    1990-
   Volume(issue)/page/year: 3,9,1992

系列性分类

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