安全信息
RTECS | TB1090000 |
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Administration onto the skin
SPECIES OBSERVED : Rodent - rabbit
DOSE/DURATION : 250 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 221
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Intramuscular
SPECIES OBSERVED : Human
DOSE/DURATION : 3200 ng/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - visual field changes
Behavioral - sleep
Gastrointestinal - nausea or vomiting
REFERENCE :
85IVAW "Possible Long-Term Health Effects of Short-Term Exposure to Chemical
Agents," National Research Council, 3 vols., Washington, DC, National
Academy Press, 1982-85 Volume(issue)/page/year: 1,E1,1982
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TYPE OF TEST : LD50 - Let
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE : Intraperitoneal
SPECIES OBSERVED : Rodent - mouse
DOSE/DURATION : 50 ug/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory
change
Lungs, Thorax, or Respiration - bronchiolar constriction
Gastrointestinal - other changes
REFERENCE :
WHOTAC World Health Organization, Technical Report Series. (WHO, 1211
Geneva, 27, Switzerland) No.1- 1950- Volume(issue)/page/year: -,39,1970
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Human
DOSE/DURATION : 30 ug/kg
TOXIC EFFECTS :
Behavioral - headache
Gastrointestinal - nausea or vomiting
Biochemical - Enzyme inhibition, induction, or change in blood or tissue
levels - true cholinesterase
REFERENCE :
85IVAW "Possib
TYPE OF TEST : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE : Subcutaneous
SPECIES OBSERVED : Rodent - rat
DOSE : 75 ug/kg
SEX/DURATION : female 6-20 day(s) after conception
TOXIC EFFECTS :
Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
resorbed implants per total number of implants)
Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death,
e.g., stunted fetus)
Reproductive - Effects on Newborn - behavioral
REFERENCE :
TJADAB Teratology, The International Journal of Abnormal Development. (Alan
R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968-
Volume(issue)/page/year: 36,25A,1987