10H-Phenothiazine, 10-(3-quinuclidinylmethyl)-,5-oxide

CAS 40765-34-2 MFCD01706744

化学结构图

40765-34-2
SMILES: O=S1C2C=CC=CC=2N(CC2CN3CCC2CC3)C2C=CC=CC1=2

化学属性

Mol. FormulaC20H22N2OS
Mol. Weight338.50

别名和识别编码

Chemical Name10H-Phenothiazine, 10-(3-quinuclidinylmethyl)-,5-oxide
Wiswesser Line NotationT C666 BN ISJ IO B1- AT66 A B CNTJ
Synonym LM-209 SO Mequitazine sulfoxide 10H-Phenothiazine, 10-(1-azabicyclo(2.2.2)oct-3-ylmethyl)-, 5-oxide
CAS Number40765-34-2
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安全信息

RTECSSP5086000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1030 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Behavioral - changes in motor activity (specific assay)
   Behavioral - ataxia
REFERENCE :
   NYKZAU Nippon Yakurigaku Zasshi.  Japanese Journal of Pharmacology. (Nippon
   Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho,
   Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40-    1944- Volume(issue)/page/year:
   78,431,1981

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