2H-1,3,2-Oxazaphosphorine,tetrahydro-2-(bis(2-chloroethyl)amino)-4-methyl-,2-oxide

CAS 52663-82-8 MFCD01710188

化学结构图

52663-82-8
SMILES: CC1CCOP(=O)(N1)N(CCCl)CCCl

化学属性

Mol. FormulaC8H17Cl2N2O2P
Mol. Weight275.14

别名和识别编码

Chemical Name2H-1,3,2-Oxazaphosphorine,tetrahydro-2-(bis(2-chloroethyl)amino)-4-methyl-,2-oxide
Wiswesser Line NotationT6MPOTJ BO BN2G2G F1
Synonym B 699 Tetrahydro-2-(bis(2-chloroethyl)amino)-4-methyl-2H-1,3,2-oxazaphosphorine 4-Methylcyclophosphamide
CAS Number52663-82-8
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安全信息

RTECSRP6152100 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   ARZNAD Arzneimittel-Forschung. Drug Research.  (Editio Cantor Verlag,
   Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.)  V.1-    1951-
   Volume(issue)/page/year: 11,143,1961

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Bird - chicken Cells - not otherwise specified
DOSE/DURATION           : 1310 ug/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 268,115,1992

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bird - chicken Cells - not otherwise specified
DOSE/DURATION           : 10500 ug/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 268,115,1992

系列性分类

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