1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol,8-(2-propynyl)-, (+-)-tropate (ester)

CAS 10139-08-9 MFCD01711262

化学结构图

10139-08-9
SMILES: C#CCN1[C@@H]2C[C@H](C[C@H]1CC2)OC(=O)C(CO)C1C=CC=CC=1 |&1:4,6,8|

化学属性

Mol. FormulaC19H23NO3
Mol. Weight313.43

别名和识别编码

Chemical Name1-alpha-H,5-alpha-H-Nortropan-3-alpha-ol,8-(2-propynyl)-, (+-)-tropate (ester)
Synonym N 1084 N-Propargylnoratropine
Beilstein Registry Number1549200
CAS Number10139-08-9
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安全信息

RTECSRD1677000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 60 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 19,52,1967

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 150 mg/kg
TOXIC EFFECTS :
   Behavioral - excitement
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 19,52,1967

系列性分类

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