Isonicotinic acid, 2-isopropylhydrazide, dihydrochloride

CAS 6011-62-7 MFCD01717804

化学结构图

6011-62-7
SMILES: CC(C)NNC(=O)c1ccncc1.Cl.Cl

化学属性

Mol. FormulaC9H13N3O.2ClH
Mol. Weight252.17

别名和识别编码

Chemical NameIsonicotinic acid, 2-isopropylhydrazide, dihydrochloride
Wiswesser Line NotationT6NJ DVMMY1&1 &GH 2
Synonym 4-Pyridinecarboxylic acid, 2-(1-methylethyl)hydrazide, dihydrochloride Iproniazid dihydrochloride Iproniazid hydrochloride
CAS Number6011-62-7
InChIKeyRXNVZODBLVJNCE-UHFFFAOYSA-N
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安全信息

RTECSNS1926000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1470 mg/kg
TOXIC EFFECTS :
   Endocrine - adrenal cortex hypoplasia
   Blood - changes in cell count (unspecified)
   Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   67,511,1960

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 3233 mg/kg
SEX/DURATION            : female 61 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - menstrual cycle changes or disorders
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   67,511,1960

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 6720 mg/kg
SEX/DURATION            : female 30 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Maternal Effects - ovaries, fallopian tubes
   Reproductive - Maternal Effects - uterus, cervix, vagina
REFERENCE :
   ENDOAO Endocrinology (Baltimore).  (Williams & Wilkins Co., 428 E. Preston
   St., Baltimore, MD 21203) V.1-    1917-  Volume(issue)/page/year:
   67,511,1960

系列性分类


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