Hydrocupreine, O(Sup 6')-isopentyl-, dihydrochloride

CAS 18984-80-0 MFCD01722139

化学结构图

18984-80-0
SMILES: Cl.Cl.CC(C)CCOC1C=CC2N=CC=C([C@@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4CC)C=2C=1

化学属性

Mol. FormulaC24H34N2O2.2ClH
Mol. Weight455.52

别名和识别编码

Chemical NameHydrocupreine, O(Sup 6')-isopentyl-, dihydrochloride
Wiswesser Line NotationT66 BNJ HO1Y2&1 EYQ- DT66 A B CNTJ A2 &GH 2
Synonym Eucupin dihydrochloride Euprocin hydrochloride 6-Quinolinol, 4-((1-methoxybutoxy)(5-vinyl-2-quinuclidinyl)methyl)-, Isoamyl hydrocupreine dihydrochloride
CAS Number18984-80-0
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安全信息

RTECSMW6660000 
TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 50 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
   Cardiac - other changes
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin.  (Berlin, Fed.
   Rep. Ger.)  V.1-139, 1913-65.  For publisher information, see REXMAS.
   Volume(issue)/page/year: 11,257,1920

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 20 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CLDND* Compilation of LD50 Values of New Drugs.  (J.R. MacDougal, Dept. of
   National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa,
   Ont., Canada)

TYPE OF TEST            : LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Mammal - cat
DOSE/DURATION           : 6820 ug/kg
TOXIC EFFECTS :
   Lungs, Thorax, or Respiration - acute pulmonary edema
   Blood - other changes
REFERENCE :
   ZGEMAZ Zeitschrift fuer die Gesamte Experimentelle Medizin.  (Berlin, Fed.
   Rep. Ger.)  V.1-139, 1913-65.  For publisher information, see REXMAS.
   Volume(issue)/page/year: 11,257,1920

{hazard

系列性分类

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