(3Ar,4R,7R,8S,9S,10R,11R,13R,15R,15Ar)-10-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-4-Ethyl-11-Hydroxy-8-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2-Yl)Oxy)-3A,7,9,11,13,15-Hexamethyloctahy (3aR,4R,7R,8S,9S,10R,11R,13R,15R,15aR)-10-(((2S,3R,4S,6R)-4-(二甲基氨基)-3-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-4-乙基-11-羟基-8-(((2R,4R,5S,6S)-5-羟基-4-甲氧基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-3a,7,9,11,13,15-六甲基八氢-3aH-[1,3]二氧杂戊环并[4,5-c][1]氧杂环十四烷-2,6,14(4H,7H)-三酮

CAS 55224-05-0 MFCD01729176

化学结构图

55224-05-0
SMILES: CO[C@]1(C)C[C@H](O[C@H]2[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H]3OC(=O)O[C@]3(C)[C@@H](CC)OC(=O)[C@@H]2C)O[C@@H](C)[C@@H]1O

化学属性

Mol. FormulaC38H65NO14
Mol. Weight760

别名和识别编码

Chemical Name(3Ar,4R,7R,8S,9S,10R,11R,13R,15R,15Ar)-10-(((2S,3R,4S,6R)-4-(Dimethylamino)-3-Hydroxy-6-Methyltetrahydro-2H-Pyran-2-Yl)Oxy)-4-Ethyl-11-Hydroxy-8-(((2R,4R,5S,6S)-5-Hydroxy-4-Methoxy-4,6-Dimethyltetrahydro-2H-Pyran-2-Yl)Oxy)-3A,7,9,11,13,15-Hexamethyloctahy
Synonym Dravercin Erythromycin A cyclic carbonate Cykliczny weglan erytromycyny A Eritromicina A carbonato CWE Erythromycin A 11,12-carbonate Davercin Carbonato ciclico de eritromicina A
CAS Number55224-05-0
Chemical Name Translation(3aR,4R,7R,8S,9S,10R,11R,13R,15R,15aR)-10-(((2S,3R,4S,6R)-4-(二甲基氨基)-3-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-4-乙基-11-羟基-8-(((2R,4R,5S,6S)-5-羟基-4-甲氧基-4,6-二甲基四氢-2H-吡喃-2-基)氧基)-3a,7,9,11,13,15-六甲基八氢-3aH-[1,3]二氧杂戊环并[4,5-c][1]氧杂环十四烷-2,6,14(4H,7H)-三酮
MDL Number
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安全信息

RTECSKF4670000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 31,241,1974

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4050 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   APPHAX Acta Poloniae Pharmaceutica.  For English translation, see APPFAR.
   (Ars Polona, POB 1001, 00-680 Warsaw 1, Poland)  V.1-    1937-
   Volume(issue)/page/year: 31,241,1974

系列性分类

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