Cytosine, 2,2'-anhydroarabino-5-fluoro-
CAS 37717-21-8 MFCD01735933
化学结构图
SMILES: N=C1N=C2O[C@@H]3[C@@H](O[C@H](CO)[C@H]3O)N2C=C1F
化学属性
| Mol. Formula | C9H10FN3O4 |
|---|---|
| Mol. Weight | 243.22 |
别名和识别编码
| Chemical Name | Cytosine, 2,2'-anhydroarabino-5-fluoro- |
|---|---|
| Wiswesser Line Notation | T B556 AN CO GO IN HHTT&J D1Q EQ JZ KF |
| Synonym | 2,2'-Anhydro-5-fluoro-1-beta-D-arabinofuranosylcytosine 2,2'-Anhydroarabino-5-fluorocytosine AAFC Flurocitabine Anhydro-ara-5-fluorocytidine NSC-166641 Ro 21-0702 |
| Beilstein Registry Number | 0891648 |
| CAS Number | 37717-21-8 |
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安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Human DOSE/DURATION : 33 mg/kg TOXIC EFFECTS : Gastrointestinal - nausea or vomiting Blood - normocytic anemia Blood - leukopenia REFERENCE : EJCAAH European Journal of Cancer. (Oxford, UK) V.1-17(6), 1965-1981. For publisher information, see EJCODS. Volume(issue)/page/year: 14,195,1978
TYPE OF TEST : DNA inhibition TEST SYSTEM : Rodent - mouse Leukocyte DOSE/DURATION : 1 mmol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,2657,1974
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