2-METHYLAMINO-4-N-METHYLPIPERAZINO-5-METHYLTHIO-6-CHLOROPYRIMIDINE HYD ROCHLORIDE
CAS 74039-21-7 MFCD01749689
化学结构图
SMILES: Cl.CN1CCN(CC1)C1N=C(NC)N=C(Cl)C=1SC
化学属性
| Mol. Formula | C11H18ClN4S.ClH |
|---|---|
| Mol. Weight | 310.30 |
别名和识别编码
| Chemical Name | Pyrimidine,6-chloro-2-methylamino-4-(4-methylpiperazino)-5-methylthio-, hydrochloride |
|---|---|
| Wiswesser Line Notation | T6N DNTJ A1 D- DT6N CNJ BM1 ES1 FG |
| Synonym | 2-Methylamino-4-N-methylpiperazino-5-methylthio-6-chloropyrimidine |
| CAS Number | 74039-21-7 |
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安全信息
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 35 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,606,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 21 mg/kg TOXIC EFFECTS : Autonomic Nervous System - sympathomimetic REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,606,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 330 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,606,1977
TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Autonomic Nervous System - ganglion blocker REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,606,1977
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