4',7-Dihydroxyflavone 7-羟基-2-(4-羟基苯基)-4H-苯并吡喃-4-酮

CAS 2196-14-7 MFCD00017694

化学结构图

2196-14-7
SMILES: O=c1cc(-c2ccc(O)cc2)oc2cc(O)ccc12

化学属性

Mol. FormulaC15H10O4
Mol. Weight254.25
Melting Point315-316 ºC
Density1.443

别名和识别编码

Chemical Name4',7-Dihydroxyflavone
Synonym 4',7-Dihydroxyflavone 4',7-Dihydroxyflavone; 7-Hydroxy-2-(4-hydroxyphenyl)chromen-4-one 4',7-dihydroxyflavone 4H-1-Benzopyran-4-one, 7-hydroxy-2-(4-hydroxyphenyl)- 7,4'-DHF 7,4'-Dihydroxyflavanone 7,4'-dihydroxyflavone 7-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
CAS Number2196-14-7
Wiswesser Line NotationT66 BO EVJ CR DQ& IQ
Beilstein Registry Number0224356
Chemical Name Translation7-羟基-2-(4-羟基苯基)-4H-苯并吡喃-4-酮
LabNetwork Molecule IDLN01360375
PubChem Substance ID5282073
InChIInChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)14-8-13(18)12-6-5-11(17)7-15(12)19-14/h1-8,16-17H
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相关文献及参考

  • [2]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2. Phytother Res. 2015 Jun;29(6):925-32.
  • [1]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts. Phytother Res. 2017 Mar;31(3):449-458.
  • [1]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Prevents Dexamethasone Paradoxical Adverse Effect on Eotaxin Production by Human Fibroblasts. Phytother Res. 2017 Mar;31(3):449-458.
  • [2]. Liu C, et al. The Flavonoid 7,4'-Dihydroxyflavone Inhibits MUC5AC Gene Expression, Production, and Secretion via Regulation of NF-κB, STAT6, and HDAC2. Phytother Res. 2015 Jun;29(6):925-32.

安全信息

RTECSLK8329000
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   FRPSAX Farmaco, Edizione Scientifica. (Casella Postale 227, 27100 Pavia,
   Italy)  V.8-43 1953-88 For publisher information, see FRMCE8
   Volume(issue)/page/year: 38,67,1983

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/plate
REFERENCE :
   ENMUDM Environmental Mutagenesis.  (New York, NY)  V.1-9, 1979-87.  For
   publisher information, see EMMUEG.  Volume(issue)/page/year: 3,401,1981

系列性分类


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