TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >5500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJRIDH European Journal of Rheumatology and Inflammation.  (Cameron
   Publishers International, Ltd., 33 Malew St., Castletown, Isle of Man, UK)
   V.1-     1978-  Volume(issue)/page/year: 4,173,1981

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJRIDH European Journal of Rheumatology and Inflammation.  (Cameron
   Publishers International, Ltd., 33 Malew St., Castletown, Isle of Man, UK)
   V.1-     1978-  Volume(issue)/page/year: 4,173,1981

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : >40 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJRIDH European Journal of Rheumatology and Inflammation.  (Cameron
   Publishers International, Ltd., 33 Malew St., Castletown, Isle of Man, UK)
   V.1-     1978-  Volume(issue)/page/year: 4,173,1981

T

TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : >100 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   EJRIDH European Journal of Rheumatology and Inflammation.  (Cameron
   Publishers International, Ltd., 33 Malew St., Castletown, Isle of Man, UK)
   V.1-     1978-  Volume(issue)/page/year: 4,173,1981

{

TYPE OF TEST            : LD - Lethal

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Intramuscular
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 2200 ug/kg
SEX/DURATION            : female 6-16 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   26,184,1973