4'-Fluoro-4-biphenylacetamide 4,4'-二氟联苯

CAS 398-32-3 MFCD00017955

化学结构图

398-32-3
SMILES: CC(=O)Nc1ccc(-c2ccc(F)cc2)cc1

化学属性

Mol. FormulaC14H12FNO
Mol. Weight229.256

别名和识别编码

Chemical Name4'-Fluoro-4-biphenylacetamide
CAS Number398-32-3
Synonym 4'-(p-Fluorophenyl)acetanilide 4'-Fluoro-4-acetylaminobiphenyl 4'-fluoro-4-biphenylacetamide N-(4'-Fluoro-4-biphenylyl)acetamide N-4-(4'-Fluoro)biphenylacetamide
MDL NumberMFCD00017955
Chemical Name Translation4,4'-二氟联苯
InChIKeyJORMZLCKCZMVJM-UHFFFAOYSA-N
Wiswesser Line NotationFR DR DMV1
Beilstein Registry Number2806508
PubChem Substance ID9812
InChIInChI=1S/C14H12FNO/c1-10(17)16-14-8-4-12(5-9-14)11-2-6-13(15)7-3-11/h2-9H,1H3,(H,16,17)
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安全信息

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 6048 mg/kg/36W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   EXPEAM Experientia.  (Birkhaeuser Verlag, POB 133, CH-4010 Basel,
   Switzerland)  V.1-    1945-  Volume(issue)/page/year: 32,217,1976

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 8064 mg/kg/48W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   JJIND8 JNCI, Journal of the National Cancer Institute.  (Washington, DC)
   V.61-79, 1978-87. For publisher information, see JNCIEQ.
   Volume(issue)/page/year: 64,1537,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4032 mg/kg/24W-C
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   AJPAA4 American Journal of Pathology.  (Lippincott/Harper, Journal
   Fulfillment Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1925-
   Volume(issue)/page/year: 100,317,1980

TYPE OF TEST            : TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 5 gm/kg/36W-I
TOXIC EFFECTS :
   Tumorigenic - equivocal tumorigenic agent by RTECS criteria
   Liver - tumors
   Kidney, Ureter, Bladder - Kidney tumors
REFERENCE :
   JNCIAM Journal of the National Cancer Institute.  (Washington, DC)  V.1-60,
   1940-78.  For publisher information, see JJIND8.

RTECSAE3750000

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