N-Benzyl-Bis(2-Chloroethyl)Amine Hydrochloride N-苄基-双邻氯乙基氨基盐酸盐

CAS 10429-82-0 MFCD00185654

化学结构图

10429-82-0
SMILES: Cl.ClCCN(CC1C=CC=CC=1)CCCl

化学属性

Mol. FormulaC11H15Cl2N·HCl
Mol. Weight269
Melting Point134-136

别名和识别编码

Chemical NameN-Benzyl-Bis(2-Chloroethyl)Amine Hydrochloride
CAS Number10429-82-0
Alfabeta NameBENZYLCHLOROCHLOROETHYLETHANAMINEHYDROCHLORIDE NN22()------
MDL NumberMFCD00185654
Synonym N-benzyl-2-chloro-N-(2-chloroethyl)ethanamine hydrochloride
Wiswesser Line NotationG2N2G1R &GH
Chemical Name TranslationN-苄基-双邻氯乙基氨基盐酸盐
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分类

  • {KO} ReacChlorides

安全信息

Warnings IRRITANT
RTECSDP1588000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 28 mg/kg
TOXIC EFFECTS :
   Blood - changes in bone marrow (not otherwise specified)
   Blood - other changes
   Reproductive - Paternal Effects - testes, epididymis, sperm duct
REFERENCE :
   CANCAR Cancer (Philadelphia).  (Lippincott/Harper, Journal Fulfillment
   Dept., 2350 Virginia Ave., Hagerstown, MD 21740)  V.1-    1948-
   Volume(issue)/page/year: 2,1055,1949

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Mold - Aspergillus nidulans
DOSE/DURATION           : 2500 umol/L
REFERENCE :
   SOGEBZ Soviet Genetics.  English translation of GNKAA5.  (Plenum Pub. Corp.,
   233 Spring St., New York, NY 10013)  V.2-    1966- Volume(issue)/page/year:
   6,220,1970

GHS Symbol
Signal word Warning
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘;
  • S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 眼睛接触后,立即用大量水冲洗并征求医生意见;
  • S28 After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) 皮肤接触后,立即用大量…(由生产厂家指定)冲洗;
  • S36/37/39 Wear suitable protective clothing, gloves and eye/face protection 穿戴适当的防护服、手套和眼睛/面保护;
  • S45 In case of accident or if you feel unwell seek medical advice immediately (show the label where possible) 发生事故时或感觉不适时,立即求医(可能时出示标签);
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P271 Use only outdoors or in a well-ventilated area.? 只能在室外或通风良好的地方使用。
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。

药物吸收、分布、代谢与排泄(ADME)

Lipinski's Rule of 5
Y
H-bond Acceptors
1
H-bond Donors
0
LogP
3

系列性分类


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