2-Chloro-5-(Trifluoromethyl)-4-Iodopyridine 2-氯-5-三氟甲基-4-碘吡啶
CAS 505084-55-9 MFCD01862099
化学结构图
SMILES: FC(F)(F)c1cnc(Cl)cc1I
化学属性
| Mol. Formula | C6H2ClF3IN |
|---|---|
| Mol. Weight | 307 |
| Melting Point | 126.0 to 130.0 deg-C |
别名和识别编码
| Chemical Name | 2-Chloro-5-(Trifluoromethyl)-4-Iodopyridine |
|---|---|
| CAS Number | 505084-55-9 |
| Alfabeta Name | CHLOROIODOTRIFLUOROMETHYLPYRIDINE 245()----- |
| MDL Number | MFCD01862099 |
| Chemical Name Translation | 2-氯-5-三氟甲基-4-碘吡啶 |
| Synonym | |
| Reaxys-RN | 9192770 |
| PubChem Substance ID | 253660602 |
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分类
- Aromatics
- Heterocycles
- {SA} Building Blocks, C6 to C7, Chemical Synthesis, Heterocyclic Building Blocks, New Products for Chemical Synthesis, Pyridines
- {SNA} Building Blocks, C6, Chemical Synthesis, Heterocyclic Building Blocks, Pyridines
产品应用
- 2-Chloro-4-iodo-5-(trifluoromethyl)pyridine is used in preparation of pyridine-2,4-diamine derivatives as FAK inhibitors for the treatment of arthritis, inflammatory and immune disorders.
相关文献及参考
- Lide, D., et al.: J. Chem. Phys., 29, 914 (1958),
- Giovannini, E., et al.: Helv. Chim. Acta, 42, 1142 (1959),
安全信息
- P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
- P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
- P302+P352+P332+P313+P362+P364
- P305+P351+P338+P337+P313
- H315 Causes skin irritation 会刺激皮肤
GHS Symbol
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