3,3'-Diiodo-L-Thyronine 3,3'-二碘甲腺原氨酸
CAS 4604-41-5 MFCD01863378
化学结构图
SMILES: N[C@@H](Cc1ccc(Oc2ccc(O)c(I)c2)c(I)c1)C(=O)O
化学属性
| Mol. Formula | C15H13I2NO4 |
|---|---|
| Mol. Weight | 525 |
别名和识别编码
| Chemical Name | 3,3'-Diiodo-L-Thyronine |
|---|---|
| CAS Number | 4604-41-5 |
| Synonym | 3,3′-二碘-L-甲腺原氨酸 (T2) O-(4-Hydroxy-3-iodophenyl)-3-iodo-L-tyrosine 3-[4-(4-Hydroxy-3-iodophenoxy)-3-iodophenyl]-L-alanine 3,3'-·Diiodo-·4-·(4-·hydroxyphenoxy)·-L-phenylalanine O-(4-·Hydroxyphenyl)-3-,3'-·diiodo-L-tyrosine T2 3,3'-T2 |
| MDL Number | MFCD01863378 |
| EC Number | 225-005-7 |
| Chemical Name Translation | 3,3'-二碘甲腺原氨酸 |
| LabNetwork Molecule ID | LN00191305 |
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分类
- Amino Acids & Derivatives
- Labeling and Diagnostics Reagents
- {SNA} Alphabetical Listings, D, Stable Isotopes, Steroids and Hormones
- {SNA} Alphabetical Listings, Bioactive Compounds, D, Stable Isotopes, Steroids and Hormones
产品应用
- Of interest for the early detection and treatment of congenital or drug-induced hypothyroidism in the developing human fetus.
相关文献及参考
- [2]. Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3,5-diiodo-L-thyronine and by 3,3'-diiodo-L-thyronine. Mol Cell Endocrinol. 1994 Feb;99(1):89-94.
- [3]. Chen X, et al. Simultaneous quantification of T4, T3, rT3, 3,5-T2 and 3,3'-T2 in larval zebrafish (Danio rerio) as a model to study exposure to polychlorinated biphenyls. Biomed Chromatogr. 2018 Jun;32(6):e4185.
- Block, P.: J. Med. Chem., 19(8), 1067-1069 (1976)
- [1]. Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3'-diiodo-L-thyronine (3,3'-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88.
- [1]. Lorenzini L, et al. Assay of Endogenous 3,5-diiodo-L-thyronine (3,5-T2) and 3,3'-diiodo-L-thyronine (3,3'-T2) in Human Serum: A Feasibility Study. Front Endocrinol (Lausanne). 2019 Feb 19;10:88.
- [2]. Lanni A, et al. Rapid stimulation in vitro of rat liver cytochrome oxidase activity by 3
安全信息
GHS Symbol
- H302 Harmful if swallowed 吞食有害
- R22 Harmful if swallowed 吞咽有害
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