1H-Pyrido(3,4-b)indol-1-one,2,3,4,9-tetrahydro-9-methyl-2-(3-(4-phenyl-1-piperazinyl) propyl)-, dihydrochloride

CAS 124824-14-2 MFCD01939920

化学结构图

124824-14-2
SMILES: Cl.Cl.CN1C2C(=O)N(CCCN3CCN(CC3)C3C=CC=CC=3)CCC=2C2C=CC=CC1=2

化学属性

Mol. FormulaC25H30N4O.2ClH
Mol. Weight475.51

别名和识别编码

Chemical Name1H-Pyrido(3,4-b)indol-1-one,2,3,4,9-tetrahydro-9-methyl-2-(3-(4-phenyl-1-piperazinyl) propyl)-, dihydrochloride
Synonym B 193 9-Methyl-2-(3-(4-phenyl-1-piperazinylpropyl))-1,2,3,4-tetrahydro-beta-carbolin-1-one 2HCl
CAS Number124824-14-2
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安全信息

RTECSUV1120000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 227 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPAE3 Polish Journal of Pharmacology.  (Polish Academy of Sciences,
   Institute of Pharmacology, Smetna 12, 31-343 Krakow, Poland)  V.45- 1993- 
   Volume(issue)/page/year: 47,305,1995

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 730 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPAE3 Polish Journal of Pharmacology.  (Polish Academy of Sciences,
   Institute of Pharmacology, Smetna 12, 31-343 Krakow, Poland)  V.45- 1993- 
   Volume(issue)/page/year: 47,305,1995

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 650 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPAE3 Polish Journal of Pharmacology.  (Polish Academy of Sciences,
   Institute of Pharmacology, Smetna 12, 31-343 Krakow, Poland)  V.45- 1993- 
   Volume(issue)/page/year: 47,305,1995

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 90 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PJPAE3 Polish Journal of Pharmacology.  (Polish Academy of Sciences,
   Institute of Pharmacology, Smetna 12, 31-343 Krakow, Poland)  V.45- 1993- 
   Volume(issue)/page/year: 47,305,1995

系列性分类

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