Pyridine,2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-,maleate (1:1), (-)-

CAS 23095-76-3 MFCD01941429

化学结构图

23095-76-3
SMILES: CN(C)CCC(C1C=CC=CN=1)C1C=CC(Cl)=CC=1.OC(=O)/C=C\C(O)=O

化学属性

Mol. Weight390.90
Mol. FormulaC16H19ClN2.C4H4O4

别名和识别编码

CAS Number23095-76-3
Chemical NamePyridine,2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-,maleate (1:1), (-)-
Synonym (-)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate (?R)-?-(4-Chlorophenyl)-N,N-dimethyl-2-pyridinepropanamine (2Z)-2-Butenedioate l-Chlorpheniramine maleate
Wiswesser Line NotationT6NJ BYR DG&2N1&1 &QV1U1VQ --
Chemical Name Translation
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分类

  • Amines
  • Chiral Reagents
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • The R-enantiomer of Chlorpheniramine (C424300). Antihistaminic.

相关文献及参考

  • Ishida, M., et al.: Int. J. Pharm., 359, 46 (2008),

安全信息

RTECSUS6502000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - guinea pig
DOSE/DURATION           : 176 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - mydriasis (pupillary dilation)
   Behavioral - tremor
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JPETAB Journal of Pharmacology and Experimental Therapeutics.  (Williams &
   Wilkins Co., 428 E. Preston St., Baltimore, MD 21202)  V.1-    1909/10-
   Volume(issue)/page/year: 124,347,1958

系列性分类

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