5-alpha-Pregnane-11,20-dione, 3-alpha,21-dihydroxy-

CAS 14107-37-0 MFCD00200115

化学结构图

14107-37-0
SMILES: C[C@]12CC(=O)[C@H]3[C@@H](CC[C@H]4C[C@H](O)CC[C@@]43C)[C@@H]1CC[C@@H]2C(=O)CO

化学属性

Mol. FormulaC21H32O4
Mol. Weight348

别名和识别编码

Chemical Name5-alpha-Pregnane-11,20-dione, 3-alpha,21-dihydroxy-
CAS Number14107-37-0
Synonym (3?,5?)-3,21-Dihydroxypregnane-11,20-dione Alfadolone 3?,21-Dihydroxy-5?-pregnane- Alphadolone 3-alpha,21-Dihydroxy-5-alpha-pregnane-11,20-dione
Chemical Name Translation
MDL Number
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids

产品应用

  • Alphadolone or Alfadolone (INN) is a neuroactive steroid with hypnotic effects. Alphadolone is one of the components of Althesin.

相关文献及参考

  • Harrison, N., et al.: J. Pharmacol. Exp. Ther., 241, 346 (1987),
  • Serrao, J., et al.: Anesthesiology, 70, 780 (1989),
  • Mistry, D., et al.: Exp. Physiol., 75, 199 (1900),

安全信息

RTECSTU4157300 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 59 mg/kg
TOXIC EFFECTS :
   Cardiac - other changes
   Lungs, Thorax, or Respiration - cyanosis
   Lungs, Thorax, or Respiration - other changes
REFERENCE :
   JEMAAJ Journal of the Egyptian Medical Association.  (Egyptian Medical
   Assoc., 42, Sharia Kasr-El- Aini, Cairo, Egypt)  V.11-    1928-
   Volume(issue)/page/year: 62,191,1979

系列性分类

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