Clofenamide 氯非那胺

CAS 671-95-4 MFCD00210257

化学结构图

671-95-4
SMILES: NS(=O)(=O)c1ccc(Cl)c(S(N)(=O)=O)c1

化学属性

Mol. FormulaC6H7ClN2O4S2
Mol. Weight270.71
Melting Point206-207 °C

别名和识别编码

Chemical NameClofenamide
CAS Number671-95-4
Synonym Clofenamide {LY} Clofenamide {} {LY} Clofenamide {} {} {LY} Clofenamide {} {} {} {LY} Clofenamide {} {} {} {} {LY} Clofenamide {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Clofenamide {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
Chemical Name Translation氯非那胺
Wiswesser Line NotationZSWR BG ESZW
Beilstein Registry Number2142672
PubChem Substance ID69594
InChIInChI=1S/C6H7ClN2O4S2/c7-5-2-1-4(14(8,10)11)3-6(5)15(9,12)13/h1-3H,(H2,8,10,11)(H2,9,12,13)
MDL NumberMFCD00210257
Canonical SMILESO=S(C1=CC(S(=O)(N)=O)=CC=C1Cl)(N)=O
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分类

  • Aromatics
  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Sulfur & Selenium Compounds

产品应用

  • Clofenamide is used as a diuretic agent.

相关文献及参考

  • Horstmann, H., et al.: Arzneim.-Forsch., 17,?653 (1967),

安全信息

RTECSCZ9100000 
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 661 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 21,775,1979

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 340 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   WRPCA2 World Review of Pest Control.  (London, UK)  V.1-10, 1962-71.
   Discontinued.  Volume(issue)/page/year: 9,119,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 1800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   YAKUD5 Gekkan Yakuji.  Pharmaceuticals Monthly.  (Yakugyo Jihosha, Inaoka
   Bldg., 2-36 Jinbo-cho, Kanda, Chiyoda-ku, Tokyo 101, Japan)  V.1-   1959-
   Volume(issue)/page/year: 21,775,1979

Storage condition

系列性分类

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