3,8-Dimethyl-3H-Imidazo[4,5-F]Quinoxalin-2-Amine 3,8-二甲基-3H-咪唑[4,5-f]喹喔啉-2-胺
CAS 77500-04-0 MFCD00210329
化学结构图
SMILES: CC1=CN=C2C=CC3=C(N=C(N)N3C)C2=N1
化学属性
| Mol. Formula | C11H11N5 |
|---|---|
| Mol. Weight | 213.27 |
别名和识别编码
| Chemical Name | 3,8-Dimethyl-3H-Imidazo[4,5-F]Quinoxalin-2-Amine |
|---|---|
| CAS Number | 77500-04-0 |
| Synonym | 2-Amino-3,8-dimethylimidazo(4,5-f)quinoxaline MeIQx 3,8-Dimethyl-3H-Imidazo[4,5-f]quinoxalin-2-amine 2-Amino-3,8-dimethyl-3H-imidazo(4,5-f)quinoxaline 3,8-Dimethyl-3H-imidazo(4,5-f)quinoxalin-2-amine |
| Chemical Name Translation | 3,8-二甲基-3H-咪唑[4,5-f]喹喔啉-2-胺 |
| Beilstein Registry Number | 4188271 |
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分类
- Heterocycles
- Mutagenesis Research Chemicals
产品应用
- Mutagen found in white meat, increasing the rate of colorectal adenomas.
相关文献及参考
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安全信息
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 8580 mg/kg/61W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Ear) - effect, not otherwise specified Liver - tumors REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 9,71,1988
TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 42336 mg/kg/84W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - leukemia REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 8,665,1987
TYPE OF TEST : DNA damage ROUTE OF EXPOSURE : Intraperitoneal TEST SYSTEM : Rodent - mouse DOSE/DURATION : 13 mg/kg REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(i
TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 70 ug/L REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 192,239,1987
TYPE OF TEST : DNA adduct ROUTE OF EXPOSURE : Oral TEST SYSTEM : Rodent - mouse DOSE/DURATION : 100 mg/kg REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 11,43,1990
TYPE OF TEST : DNA adduct TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 40 umol/L REFERENCE : CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham
TYPE OF TEST : Body fluid assay TEST SYSTEM : Rodent - mouse Bacteria - Salmonella typhimurium DOSE/DURATION : 40 ug/kg REFERENCE : FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 29,377,1991
TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 5 ng/plate REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 144,131,1985
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