Olaquindox 奥拉多司

CAS 23696-28-8 MFCD00210341

化学结构图

23696-28-8
SMILES: CC1C(C(=O)NCCO)=[N+]([O-])C2C=CC=CC=2[N+]=1[O-]

化学属性

Mol. FormulaC12H13N3O4
Mol. Weight263
Appearance 奥拉多司(23696-28-8)为浅黄色结晶性粉末。熔点209℃（分解）。微溶于水，不溶于多数有机溶剂，稳定性好。
Melting Point209

别名和识别编码

Chemical NameOlaquindox
CAS Number23696-28-8
Synonym 2-(N-(2-Hydroxyethyl)karbamoyl)-3-methylchinoxalin-1,4-dioxid Olaquindox 喹乙醇
MDL NumberMFCD00210341
PubChem Substance ID24860694
EC Number245-832-7
Chemical Name Translation奥拉多司
Wiswesser Line NotationT66 BN ENJ BO CVM2Q D1 EO
Beilstein Registry Number0758489
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分类

  • {SNA} Analytical Standards, Antibiotics Standards, Pharmaceuticals, Illicit Drugs & Alcohol, 分析/色谱
  • Nitric Oxide Reagents
  • {SNA} Alphabetic, Analytical Standards, Analytical/Chromatography, O
  • Pharmaceuticals
  • {Chemicalbook} 饲料添加剂: 抗均促生长剂
  • {SNA} Alphabetical Index of Analytical Standards, Analytical Standards, Analytical/Chromatography, O
  • Intermediates & Fine Chemicals,

产品应用

  • A growth stimulant.

相关文献及参考

  • Barber, R.S., et al.: Anim. Feed Sci. Technol., 4, 117 (1979),
  • Kwaga, J., et al.: Antimicrob. Agents Chemother., 34, 2423 (1990),

安全信息

RTECSVD1582000
GHS Symbol
Precautionary statements
  • P261 Avoid breathing dust/fume/gas/mist/vapours/spray. 避免吸入粉尘/烟/气体/烟雾/蒸汽/喷雾。
  • P342+P311
Hazard statements
  • H302 Harmful if swallowed 吞食有害
  • H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled 吸入可能导致过敏或哮喘症状或呼吸困难
WGK Germany3
Signal word Danger
Personal Protective Equipment dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Hazard Codes Xn
Safety Statements
  • S22 Do not breathe dust 不要吸入粉尘；
  • S36/37 Wear suitable protective clothing and gloves 穿戴适当的防护服和手套；
Risk Statements
  • R22 Harmful if swallowed 吞咽有害
  • R42 May cause sensitisation by inhalation 吸入会产生过敏反应
  • R43 May cause sensitisation by skin contact 皮肤接触会产生过敏反应
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 3316 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 30,26,1981

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 1717 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   CKFRAY Ceskoslovenska Farmacie.  (PNS-Ustredni Expedice a Dovoz Tisku,
   Kafkova 19, 160 00 Prague 6, Czechoslovakia)  V.1-    1952-
   Volume(issue)/page/year: 30,26,1981

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 117,311,1983

TYPE OF TEST            : Sister chromatid exchange
TEST SYSTEM             : Rodent - hamster Lung
DOSE/DURATION           : 20 mg/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 139,199,1984

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 380 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 221,263,1989

{hazard_com

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Bacteria - Escherichia coli
DOSE/DURATION           : 1 umol/L
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 203,81,1988

TYPE OF TEST            : DNA repair
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 100 ug/disc
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 90,49,1981

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Intraperitoneal
TEST SYSTEM             : Rodent - rat
DOSE/DURATION           : 120 mg/kg
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year

系列性分类

  1. Analytical & Chromatography 分析化学与色谱
  2. Analytical Standards
  3. Alphabetic - Analytical Standards
  4. O - Alphabetic
  1. Functional Group 官能团索引
  2. N-oxide

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