Mibolerone 米勃龙

CAS 3704-09-4 MFCD00221774

化学结构图

3704-09-4
SMILES: C[C@@H]1CC2=CC(=O)CC[C@@H]2[C@H]2CC[C@@]3(C)[C@@H](CC[C@]3(C)O)[C@@H]21

化学属性

Mol. FormulaC20H30O2
Mol. Weight302.50

别名和识别编码

Chemical NameEstr-4-en-3-one, 17-beta-hydroxy-7-alpha,17-dimethyl-
CAS Number3704-09-4
Synonym (7?,17?)-17-Hydroxy-7,17-dimethylestr-4-en-3-one (7a,17)-17-Hydroxy-7,17-dimethylestr-4-en-3-one (7a,17b)-17-Hydroxy-7,17-dimethylestr-4-en-3-one 17,17-dimethyl-19-nortestosterone 17-HYDROXY-7,17-DIMETHYL-ESTR-4-EN-3-ONE 17-beta-Hydroxy-7-alpha,17-dimethylestr-4-en-3-one 17-beta-hydroxy-7-alpha,17-dimethyl-estr-4-en-3-on 17-hydroxy-7,17-dimethyl-,(7-alpha,17-beta)-estr-4-en-3-on 17BETA-HYDROXY-7ALPHA,17-DIMETHYLESTR-4-EN-3-ONE 4-ESTREN-7-ALPHA, 17-ALPHA-DIMETHYL-17-BETA-OL-3-ONE 7?,17?-Dimethyl-19-nortestosterone 7a,17a-Dimethyl-19-nortestosterone 7a,17a-dimethyl-19-nortestosterone Chequ Cheque Cheque Drops Estr-4-en-3-one, 17-hydroxy-7,17-dimethyl-, (7-alpha,17-beta)- MIBOLERONE Matenon Mebolone U-1
MDL NumberMFCD00221774
EC Number223-046-5
Chemical Name Translation米勃龙
Wiswesser Line NotationL E5 B666 OVTJ E1 FQ F1 K1
Beilstein Registry Number5565683
PubChem Substance ID251636
InChIInChI=1S/C20H30O2/c1-12-10-13-11-14(21)4-5-15(13)16-6-8-19(2)17(18(12)16)7-9-20(19,3)22/h11-12,15-18,22H,4-10H2,1-3H3/t12-,15+,16-,17+,18-,19+,20+/m1/s1
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分类

  • Pharmaceuticals
  • Intermediates & Fine Chemicals
  • Steroids,

产品应用

  • Synthetic anabolic steroid related to testosterone.

相关文献及参考

  • Campbell, J.A., et al.: Steroids, 1, 317 (1963); Hamlin, W.E., et al.: J. Pharm. Sci., 54, 1651 (1965); Sokolowski, J.H., et al.: J. Am. Vet. Med. Assoc., 173, 983 (1978),

安全信息

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE/DURATION           : 8985 ug/kg/9.6Y-I
TOXIC EFFECTS :
   Tumorigenic - neoplastic by RTECS criteria
   Reproductive - Tumorigenic effects - ovarian tumors
REFERENCE :
   TOPADD Toxicologic Pathology.  (c/o Dr. F.A. de la Iglesia, Warner-Lambert
   Co., Pharmaceutical Research Div., POB 1047, Ann Arbor, MI 48106) V.6(3/4)- 
     1978-  Volume(issue)/page/year: 13,177,1985

RTECSKG7980000 
TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - mouse
DOSE                    : 800 ug/kg
SEX/DURATION            : female 10 day(s) pre-mating
TOXIC EFFECTS :
   Reproductive - Fertility - female fertility index (e.g. # females pregnant
   per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
   STEDAM Steroids.  (Holden-Day Inc., 4432 Telegraph Ave., Oakland, CA 94609)
   V.1-    1963-  Volume(issue)/page/year: 9,235,1967

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Mammal - dog
DOSE                    : 196 ug/kg
SEX/DURATION            : female 6-61 day(s) after conception
                          lactating female 42 day(s) post-birth
TOXIC EFFECTS :
   Reproductive - Specific Developmental Abnormalities - urogenital system
REFERENCE :
   AJVRAH American Journal of Veterinary Research.  (American Veterinary
   Medical Assoc., 930 N. Meacham Rd., Schaumburg, IL 60196)  V.1-    1940-
   Volume(issue)/page/year: 39,837,1978

Hazard statements
  • H360 May damage fertility or the unborn child 可能对生育能力或未出生婴儿造成伤害
Precautionary statements
  • P201 Obtain special instructions before use. 使用前获取专门指示。
  • P202 Do not handle until all safety precautions have been read and understood. 已阅读并理解所有的安全预防措施之前，切勿操作。
  • P203
  • P280 Wear protective gloves/protective clothing/eye protection/face protection. 戴防护手套/防护服/眼睛的保护物/面部保护物。
  • P281 Use personal protective equipment as required. 使用所需的个人防护装备。
  • P308+P313
  • P318
  • P405 Store locked up. 上锁保管。
  • P501 Dispose of contents/container to..… 处理内容物/容器.....

其他信息

  • MOL 文件:3704-09-4.mol

系列性分类

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