Diethylcarbamazine 1-二乙胺基甲酰基-4-甲基哌嗪

CAS 90-89-1 MFCD00023288

化学结构图

90-89-1
SMILES: CCN(CC)C(=O)N1CCN(C)CC1

化学属性

Mol. FormulaC10H21N3O
Mol. Weight199.29
Melting Point65-67 °C
Boiling Point127-129 °C at 10 mmHg

别名和识别编码

Chemical NameDiethylcarbamazine
Synonym Diethylcarbamazine {LY} Diethylcarbamazine Diethylcarbamazine Citrate Diethylcarbamazine Citrate (1:1) Diethylcarbamazine Citrate (1:2) Diethylcarbamazine L-Tartrate (1:1) Diethylcarbamazine Maleate Diethylcarbamazine Monohydrochloride Diethylcarbamazine Phosphate (1:1) Hetrazan Loxuran Maleate, Diethylcarbamazine Monohydrochloride, Diethylcarbamazine Notezine {} {LY} Diethylcarbamazine {} {} {LY} Diethylcarbamazine {} {} {} {LY} Diethylcarbamazine {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} Diethylcarbamazine {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
CAS Number90-89-1
Beilstein Registry Number0143029
LabNetwork Molecule IDLN01325414
Chemical Name Translation1-二乙胺基甲酰基-4-甲基哌嗪
PubChem Substance ID3052
InChIInChI=1S/C10H21N3O/c1-4-12(5-2)10(14)13-8-6-11(3)7-9-13/h4-9H2,1-3H3
Canonical SMILESO=C(N1CCN(C)CC1)N(CC)CC
MDL NumberMFCD00023288
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分类

  • {uni_hamburg} no charge; nitrogen heterocycle; alicycle; 6RingOnly; 6ring; urea; 1fragment

相关文献及参考

  • Short: IV/8A Title: Enthalpies of Fusion and Transition of Organic Compounds Author: Zhang, Z.-Y.; Frenkel, M.; March, K.N.; Wilhoit, R.C. Editor: Marsh, K.N. Source: Landolt-Börnstein, New Series Volume: IV/8A Year: 1995 Keyword: organic compounds; enthaly of fusion; melting point; phase transition ISBN: 3-540-58854-X ISBN: 978-3-540-58854-2 Internet Resource: DOI:10.1007/b55145 RefComment: VIII, 588 pages.
  • Short: EINECS Title: EINECS (European Inventory of Existing Commercial Chemical Substances) Source: Official Journal of the European Communities Volume: C 146 A (15.06.1990) Page: 1 Year: 1990 Internet Resource: http://ecb.jrc.ec.europa.eu/esis/index.php?PGM=ein Publish_Date: 1990/06/15

安全信息

RTECSTL1200000
TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 240 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   JPPMAB Journal of Pharmacy and Pharmacology.  (Pharmaceutical Soc. of Great
   Britain, 1 Lambeth High St., London SEI 7JN, UK)  V.1-    1949-
   Volume(issue)/page/year: 22,306,1970

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Human - woman
DOSE/DURATION           : 7300 mg/kg/1Y-I
TOXIC EFFECTS :
   Skin and Appendages - dermatitis, allergic (after systemic exposure)
REFERENCE :
   BMJOAE British Medical Journal.  (British Medical Assoc., BMA House,
   Tavistock Sq., London WC1H 9JR, UK)  V.1-    1857- Volume(issue)/page/year:
   291,632,1985

TYPE OF TEST            : Cytogenetic analysis
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 40 mg/kg
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 44,7,1988

TYPE OF TEST            : Mutation test systems - not otherwise specified
TEST SYSTEM             : Non-mammalian species
DOSE/DURATION           : 10 mmol/L
REFERENCE :
   CUSCAM Current Science.  (Current Science Assoc., Sadashivanagar P.O.,
   Bangalore 560 080, India) V.1-    1932-  Volume(issue)/page/year:
   52,303,1983

TYPE OF TEST            : Micronucleus test
ROUTE OF EXPOSURE       : Oral
TEST SYSTEM             : Rodent - mouse
DOSE/DURATION           : 20 mg/kg
REFERENCE :
   TOLED5 Toxicology Letters.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1977-  Volume(issue)/page/year: 44,7,1988

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 630 mg/kg
SEX/DURATION            : female 7-11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Effects on Embryo or Fetus - fetal death
REFERENCE :
   CYLPDN Zhongguo Yaoli Xuebao.  Acta Pharmacologica Sinica.  Chinese Journal
   of Pharmacology.  (China International Book Trading Corp., POB 2820,
   Beijing, Peop. Rep. China)  V.1-    1980-  Volume(issue)/page/year:
   4,201,1983

Hazard statements
  • H302 Harmful if swallowed 吞食有害
Precautionary statements
  • P264 Wash hands thoroughly after handling. 处理后要彻底洗净双手。
  • P270 Do not eat, drink or smoke when using this product. 使用本产品时不要吃东西,喝水或吸烟。
  • P301+P312
  • P301+P317
  • P330 Rinse mouth. 漱口
  • P501 Dispose of contents/container to..… 处理内容物/容器.....
Storage condition RT, sealed storage, away from moisture and light {LY} RT, sealed storage, away from moisture and light {} {LY} RT, sealed storage, away from moisture and light {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and light {} {} {} {} {} {} {} {} {} {} {} {} {LY} RT, sealed storage, away from moisture and l

系列性分类


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