5-((2-Methoxyphenoxy)methyl)oxazolidin-2-one 美芬诺酮

CAS 70-07-5 MFCD00242850

化学结构图

70-07-5
SMILES: COc1ccccc1OCC1CNC(=O)O1

化学属性

Mol. FormulaC11 H13 N O4
Mol. Weight223.23

别名和识别编码

Chemical Name5-((2-Methoxyphenoxy)methyl)oxazolidin-2-one
CAS Number70-07-5
Synonym 5-(o-Methoxyphenoxymethyl)-2-oxazolidinone 5-(o-Methoxyphenoxymethyl)-2-oxazolidone 5-[(2-Methoxyphenoxy)-methyl]-2-oxazolidinone 5-[(2-Methoxyphenoxy)methyl]-2-oxazolidinone AHR 233 Alkapol peg-400 CL 27,319 Control-OM Dorsiflex Dorsilon Ekilan Lenetran Lenetran TAB Lenetranat Mefenoxalona Mefenoxalone Mephenoxalone {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {
EC Number200-723-3
Chemical Name Translation美芬诺酮
Wiswesser Line NotationT5MVOTJ D1OR BO1
Beilstein Registry Number0530698
LabNetwork Molecule IDLN01286367
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分类

  • Aromatics
  • Heterocycles
  • Pharmaceuticals
  • Intermediates & Fine Chemicals

产品应用

  • Muscle relaxant, also used as a mild tranquilizer.

相关文献及参考

  • Erk N., et al.: J. Pharm. Biomed. Anal., 21, 429(1999),

安全信息

RTECSRQ3500000 
TYPE OF TEST            : LD - Lethal dose
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : >1 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans
   Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium)  V.4-   
   1898-  Volume(issue)/page/year: 134,198,1961

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3820 mg/kg
TOXIC EFFECTS :
   Sense Organs and Special Senses (Eye) - ptosis
   Behavioral - changes in motor activity (specific assay)
   Lungs, Thorax, or Respiration - respiratory depression
REFERENCE :
   TXAPA9 Toxicology and Applied Pharmacology.  (Academic Press, Inc., 1 E.
   First St., Duluth, MN 55802) V.1-    1959-  Volume(issue)/page/year:
   6,642,1964

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : >5 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   PSDTAP Proceedings of the European Society for the Study of Drug Toxicity.
   (Princeton, NJ 08540) V.1-15, 1963-74.  For publisher information, see
   PESTD5.  Volume(issue)/page/year: 11,212,1970

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 800 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   RAMAAB Revista de la Asociacion Medica Argentina.  (Buenos Aires, Argentina)
    V.1-89, 1915-76. Discontinued.  Volume(issue)/page/year: 74,82,1960

Storage condition -20 -20°C -20℃

系列性分类

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