• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Analytical Reagents, Analytical/Chromatography, Mass Spectrometry (MS), Matrix Substances for MALDI-MS, Spectroscopy
• {SNA} Mass Spectrometry (MS), Matricies for Mass Spectroscopy Analysis of Glycans, Matrix Substances for MALDI-MS, Spectroscopy, 分子生物学, 分析/色谱, 分析试剂, 多糖标记和分析, 糖生物学, 翻译后修饰, 蛋白质组学
• {SNA} Analytical Reagents, Analytical/Chromatography, Mass Spectrometry (MS), Matricies for Mass Spectroscopy Analysis of Glycans, Matrix Substances for MALDI-MS,
• {SNA} Armoracia rusticana (Horseradish),
• {SNA} Mass Spectrometry (MS), Matrix Substances for MALDI-MS, Spectroscopy, 分析/色谱,

产品应用

• D104393:阿斯匹林代谢物。龙胆酸本身是一种解热镇痛药，也用作医药中间体。
• D119198:最常用的碳水化合物基质。用于 MALDI-MS 分析游离中性多糖。生成钠离子峰，可能有弱钾离子峰。通过加入合适的无机盐可生成其他物质。

相关文献及参考

• [2]. IS Fernández, et al. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. Journal of Biological Chemistry , 2010, 285(15):11714-29.
• Merck: 14,4398
• Merck: 14,4398 Beilstein: 10,IV,1441
• [1]. Levy G, et al. Salicylate accumulation kinetics in man. N Engl J Med. 1972 Aug 31;287(9):430-2.
• [1]. Levy G, et al. Salicylate accumulation kinetics in man. N Engl J Med. 1972 Aug 31;287(9):430-2.
• [2]. IS Fernández, et al. Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors. Journal of Biological Chemistry , 2010, 285(15):11714-29.

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 3 gm/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BCFAAI Bollettino Chimico Farmaceutico.  (Societa Editoriale Farmaceutica,
   Via Ausonio 12, 20123 Milan, Italy)  V.33-    1894- Volume(issue)/page/year:
   112,53,1973

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 4500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   BJPCAL British Journal of Pharmacology and Chemotherapy.  (London, UK)
   V.1-33, 1946-68.  For publisher information, see BJPCBM.
   Volume(issue)/page/year: 8,30,1953

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intravenous
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 374 mg/kg
TOXIC EFFECTS :
   Behavioral - convulsions or effect on seizure threshold
REFERENCE :
   JAPMA8 Journal of the American Pharmaceutical Association, Scientific
   Edition.  (Washington, DC) V.29-49, 1940-60.  For publisher information, see
   JPMSAE.  Volume(issue)/page/year: 42,254,1953

TYPE OF TEST            : DNA inhibition
TEST SYSTEM             : Human Lymphocyte
DOSE/DURATION           : 1 mmol/L
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   29,1275,1980

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 380 mg/kg
SEX/DURATION            : female 9 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
REFERENCE :
   BCPCA6 Biochemical Pharmacology.  (Pergamon Press Inc., Maxwell House,
   Fairview Park, Elmsford, NY 10523)  V.1-    1958-  Volume(issue)/page/year:
   22,407,1973

TYPE OF TEST            : TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE       : Subcutaneous
SPECIES OBSERVED        : Rodent - rat
DOSE                    : 642 mg/kg
SEX/DURATION            : female 11 day(s) after conception
TOXIC EFFECTS :
   Reproductive - Fertility - post-implantation mortality (e.g. dead and/or
   resorbed implants per total number of implants)
   Reproductive - Specific Developmental Abnormalities - musculoskeletal system
REFERENCE :
   RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD
   Pub. Ltd., P.O. Box 966, Westbury, NY 11590)  V.1-    1970-
   Volume(issue)/page/year: 38,209,1982

其他信息

• 在空气中不稳定。遇三氯化铁呈蓝色。能还原斐林氏和多伦(Tollen's)试剂。溶于水、乙醇和乙醚，几乎不溶于二硫化碳、氯仿和苯。200℃开始升华。低毒，半数致死量(大鼠，经口)800mg/kg。有刺激性。
• Sigma Aldrich:490-79-9(sigmaaldrich)
• 用途二:阿斯匹林代谢物。龙胆酸本身是一种解热镇痛药，也用作医药中间体。
• 2,5-二羟基苯甲酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/08/23 xw010424 2，5-二羟基苯甲酸;龙胆酸; 5-羟基水杨酸 25g 198元 2011/04/16 D0569 2,5-二羟基苯甲酸 2,5-Dihydroxybenzoic Acid 25G 400元 2011/04/16 D0569 2,5-二羟基苯甲酸 2,5-Dihydroxybenzoic Acid 500G 4000元
• 用途一:龙胆酸本身是一种解热镇痛药，也用作医药中间体
• 下游产品:氟卡尼
• 方法一:由对苯二酚经羟基化而得。
• TCI Shanghai:2,5-二羟基苯甲酸[基质辅助的激光解吸电离飞行时间质谱的基质] 2,5-Dihydroxybenzoic Acid [Matrix for MALDI-TOF/MS],>;99.0%(GC)(T)(490-79-9)
• 上游原料:1,4-苯二酚
• 白色针状或棱柱状结晶.在空气中不稳定.遇三氯化铁呈蓝色.能还原斐林氏和多伦(Tollen's)试剂.溶于水、乙醇和乙醚,几乎不溶于二硫化碳、氯仿和苯.200℃开始升华.低毒,半数致死量(大鼠,经口)800mg/kg.有刺激性.
• MOL 文件:490-79-9.mol
• Acros Organics:2，5-二羟基苯甲酸 2,5-Dihydroxybenzoic acid, 99%(490-79-9)
• Alfa Aesar:2,5-二羟基苯甲酸,99% 2,5-Dihydroxybenzoic acid, 99%(490-79-9)
• 外观性质:灰白色粉末。
• 海关编码:29182990
• Hazard Note:Harmful
• 图谱信息:2,5-二羟基苯甲酸(490-79-9)红外图谱(IR1) 2,5-二羟基苯甲酸(490-79-9)红外图谱(IR2) 2,5-二羟基苯甲酸(490-79-9)核磁图( 13 CNMR) 2,5-二羟基苯甲酸(490-79-9)质谱(MS)
• MSDS 信息:2,5-二羟基苯甲酸(490-79-9).msds