3-Iodo-L-tyrosine 3-碘-L-酪氨酸

CAS 70-78-0 MFCD00002608

化学结构图

70-78-0
SMILES: N[C@@H](Cc1ccc(O)c(I)c1)C(=O)O

化学属性

Mol. FormulaC9H10INO3
Mol. Weight307.09
Density1.944
Melting Point210°C
Stability对光敏感
Solubilitydilute aqueous acid: soluble
Boiling Point391°C at 760 mmHg

别名和识别编码

Chemical Name3-Iodo-L-tyrosine
CAS Number70-78-0
Synonym H-Tyr(3-I)-OH {LY} H-Tyr(3-I)-OH {} {LY} H-Tyr(3-I)-OH {} {} {LY} H-Tyr(3-I)-OH {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} H-Tyr(3-I)-OH {} {} {} {} {} {} {} {} {} {} {}
EC Number200-744-8
Beilstein Registry Number2941266
MDL NumberMFCD00002608
PubChem Substance ID439744
Reaxys-RN2941266
Merck Number5047
Chemical Name Translation3-碘-L-酪氨酸
LabNetwork Molecule IDLN00194297
InChIInChI=1S/C9H10INO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)/t7-/m0/s1
Canonical SMILESO=C(O)[C@@H](N)CC1=CC=C(O)C(I)=C1
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分类

  • {SNA} Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, I, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase
  • Inhibitors
  • Amino Acids & Derivatives
  • Chiral Reagents
  • {SNA} Enzyme Inhibitors, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase, 细胞信号转导和神经科学, 细胞生物学
  • {SNA} Bioactive Small Molecules, Cell Signaling and Neuroscience, Enzyme Inhibitors, I, Neuroscience, Neurotransmission, Neurotransmitter Metabolism, Tyrosine Hydroxylase,

产品应用

  • 酪氨酸羟化酶抑制剂。

相关文献及参考

  • [2]. D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;30(2):153-61.
  • Fitzpatrick, P.F., Steady-state kinetic mechanism of rat tyrosine hydroxylase. Biochemistry 30 , 3658-3662, (1991) 摘要
  • Fitzpatrick, P.F., et al.: Biochemistry, 30, 3658 (1991),
  • Harsing, L.G., et al.: Neuroscience, 77, 419 (1997),
  • Merck 14 ,5047
  • Merck: 14,5047 Beilstein: 14,IV,2369
  • [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.
  • [1]. GOLDSTEIN M, et al. INHIBITION OF TYROSINE HYDROXYLASE BY 3-IODO-L-TYROSINE. Life Sci (1962). 1965 Jan;4:261-4.
  • [2]. D K Ness, et al. Effects of 3-iodo-L-tyrosine, a tyrosine hydroxylase inhibitor, on eye pigmentation and biogenic amines in the planarian, Dugesia dorotocephala. Fundam Appl Toxicol. 1996 Apr;3

安全信息

Signal word Warning
GHS Symbol
WGK Germany3
Safety Statements
  • S24/25 Avoid contact with skin and eyes 避免皮肤和眼睛接触；
Risk Statements
  • R36/37/38 Irritating to eyes, respiratory system and skin 对眼睛、呼吸系统和皮肤有刺激性
Precautionary statements
  • P262 Do not get in eyes, on skin, or on clothing. 不要接触眼睛，皮肤或衣服。
Personal Protective Equipment Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Storage condition -20°C {LY} -20°C 0-10 0-10°C 2-8°C 2-8°C 避光储存 {} {LY} -20°C {} {} {LY} -20°C {} {} {} {LY} -20°C {} {} {} {} {LY} -20°C {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} { {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {LY} -20°C {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {} {}

其他信息

  • Acros Organics:3-碘-L-酪氨酸 3-Iodo-L-tyrosine, 97%(70-78-0)
  • TCI Shanghai:3-碘-L-酪氨酸 3-Iodo-L-tyrosine,>;99.0%(T)(70-78-0)
  • 3-碘-L-酪氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2011/04/16 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 1G 515元 2011/04/16 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 5G 1680元 2010/06/21 122440010 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 97% 1 GR 470元
  • 3-碘-L-酪氨酸价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2014/06/02 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 1G 488元 2014/06/02 I0075 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 5G 1600元 2010/06/21 122440010 3-碘-L-酪氨酸 3-Iodo-L-tyrosine 97% 1 GR 470元
  • MOL 文件:70-78-0.mol
  • Sigma Aldrich:70-78-0(sigmaaldrich)
  • F:8-10-23
  • 溶于15份沸水。

系列性分类

  1. Life Science 生命科学
  2. Cell Biology 细胞生物学
  3. Cell Signaling and Neuroscience - Cell Biology
  4. Neuroscience - Cell Signaling and Neuroscience
  5. Neurotransmission - Neuroscience
  6. Neurotransmitter Metabolism - Neurotransmission
  7. Enzyme Inhibitors - Neurotransmitter Metabolism
  8. Tyrosine Hydroxylase - Enzyme Inhibitors
  1. Chemical Synthesis 化学合成
  2. Chemical Biology 生物化学
  3. Peptide Chemistry 多肽化学
  4. Unnatural Amino Acid Derivatives 人工合成氨基酸
  5. Tyrosine Derivatives - Unnatural Amino Acid Derivatives
  1. Life Science 生命科学
  2. Biochemicals and Reagents
  3. Cell Signaling and Neuroscience
  4. Neuroscience
  5. Neurotransmission
  6. Neuropeptides
  7. Angiotensin Metabolism
  1. Medical Research Areas
  2. Metabolism
  3. Endogenous Metabolite  (内源性代谢物)

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