2-氨基-3,7,8-三甲基-3H -咪唑并[4,5 - f]喹喔啉 2-氨基-3,7,8-三甲基-3H -咪唑并[4,5 - f]喹喔啉

CAS 92180-79-5 MFCD00269905

化学结构图

92180-79-5
SMILES: CC1=NC2C=CC3=C(N=C(N)N3C)C=2N=C1C

化学属性

Mol. FormulaC12H13N5
Mol. Weight227

别名和识别编码

Chemical Name3H-Imidazo(4,5-f)quinoxalin-2-amine, 3,7,8-trimethyl-
CAS Number92180-79-5
Synonym 3,7,8-Trimethyl-3H-imidazo[4,5-f]quinoxalin-2-amine 7,8-DiMeIQx 3,7,8-Trimethyl-3H-imidazo(4,5-f)quinoxalin-2-amine 2-Amino-3,7,8-trimethylimidazo(4,5-f)quinoxaline
Chemical Name Translation2-氨基-3,7,8-三甲基-3H -咪唑并[4,5 - f]喹喔啉
Beilstein Registry Number6062569
MDL NumberMFCD00269905
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分类

  • Heterocycles
  • Mutagenesis Research Chemicals

产品应用

  • A mutagenic/carcinogenic heterocyclic amine under moderate conditions such as 37?C and 50?C.

相关文献及参考

  • Sugimura, T., et al.: Mutation Research, 290, 43 (1993),
  • Eisenbrand & Tang: Toxicology, 84, 1 (1993),

安全信息

RTECSNJ5924010 
TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 2500 nmol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12,53,1988

TYPE OF TEST            : Mutation in microorganisms
TEST SYSTEM             : Bacteria - Salmonella typhimurium
DOSE/DURATION           : 1 ug/plate
REFERENCE :
   MUREAV Mutation Research.  (Elsevier Science Pub. B.V., POB 211, 1000 AE
   Amsterdam, Netherlands) V.1-    1964-  Volume(issue)/page/year: 178,25,1987

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - mouse Liver
DOSE/DURATION           : 250 umol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12,53,1988

TYPE OF TEST            : Unscheduled DNA synthesis
TEST SYSTEM             : Rodent - rat Liver
DOSE/DURATION           : 25 umol/L
REFERENCE :
   EMMUEG Environmental and Molecular Mutagenesis.  (Alan R. Liss, Inc., 41 E.
   11th St., New York, NY 10003)  V.10-    1987-  Volume(issue)/page/year:
   12,53,1988

TYPE OF TEST            : DNA adduct
TEST SYSTEM             : Human Mammary gland
DOSE/DURATION           : 500 umol/L
REFERENCE :
   CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House,
   Southfield Road, Eynsham, Oxford OX8 1JJ, UK)  V.1-    1980-
   Volume(issue)/page/year: 17,1769,1996

系列性分类

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