• 原料直供
• 试剂商城
• 直接询价

分类

• {SNA} Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds
• {uni_hamburg} no charge; alcohol; 1fragment
• Amino Alcohols, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds

产品应用

• 主要用作乳化剂和酸性气体吸收剂、酸碱控制剂、聚氨酯泡沫催化剂。也用作抗肿瘤药物盐酸氮芥等的中间体。

相关文献及参考

• Beilstein: 4,IV,1517
• Reagent for protection of boronic acids as N-methyl-O,O-diethanolamine esters (cf Diethanolamine, A13389). The resulting derivatives have been converted to fluoroaromatics using cesium fluoroxysulfate: Synlett, 761 (1990); Tetrahedron, 48, 8073 (1992).
• The boronic esters are also stable in the presence of organometallic (e.g. lithium derivatives): J. Org. Chem., 54, 4734 (1989).
• Short: III/35B
• Short: III/38B

安全信息

GHS Symbol

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Oral
SPECIES OBSERVED        : Rodent - rat
DOSE/DURATION           : 4780 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 10,61,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Administration onto the skin
SPECIES OBSERVED        : Rodent - rabbit
DOSE/DURATION           : 5990 uL/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   AMIHBC AMA Archives of Industrial Hygiene and Occupational Medicine.
   (Chicago, IL)  V.2-10, 1950-54. For publisher information, see AEHLAU.
   Volume(issue)/page/year: 10,61,1954

TYPE OF TEST            : LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE       : Intraperitoneal
SPECIES OBSERVED        : Rodent - mouse
DOSE/DURATION           : 500 mg/kg
TOXIC EFFECTS :
   Details of toxic effects not reported other than lethal dose value
REFERENCE :
   NTIS** National Technical Information Service.  (Springfield, VA 22161)
   Formerly U.S. Clearinghouse for Scientific & Technical Information.
   Volume(issue)/page/year: AD277-689

其他信息

• Sigma Aldrich:105-59-9(sigmaaldrich)
• N-甲基二乙醇胺价格(试剂级):更新日期 产品编号 产品名称 包装 价格 2010/06/21 126720025 N-甲基二乙醇胺 N-Methyldiethanolamine 99+% 2.5 KG 2474元 2010/06/21 126720010 N-甲基二乙醇胺 N-Methyldiethanolamine 99+% 1 KG 1100元 2010/06/21 126722500 N-甲基二乙醇胺 N-Methyldiethanolamine 99+% 250 GR 397元
• 用途一:主要用作乳化剂和酸性气体吸收剂、酸碱控制剂、聚氨酯泡沫催化剂。也用作抗肿瘤药物盐酸氮芥等的中间体。
• 蒸气压:0.01 mm Hg ( 20 °C)
• 下游产品:高效脱硫剂
• 上游原料:二乙醇胺 --> 3-羟基丙腈
• MOL 文件:105-59-9.mol
• Acros Organics:n-甲基二乙醇胺 N-Methyldiethanolamine, 99+%(105-59-9)
• 能与水；醇混溶，微溶于醚。
• 图谱信息:N-甲基二乙醇胺(105-59-9)红外图谱(IR2) N-甲基二乙醇胺(105-59-9)质谱(MS) N-甲基二乙醇胺(105-59-9)核磁图( 13 CNMR) N-甲基二乙醇胺(105-59-9)红外图谱(IR1) N-甲基二乙醇胺(105-59-9)核磁图( 1 HNMR) N-甲基二乙醇胺(105-59-9)Raman光谱
• Alfa Aesar:N-甲基二乙醇胺,98+% N-Methyldiethanolamine, 98+%(105-59-9)
• 方法一:1.由甲醛与二乙醇胺反应而得。将甲酸加入反应锅内加热至沸，在搅拌下滴加甲醛和二乙醇胺的混合液，约1h滴完，温度维持在90-98℃，继续回流4h。然后进行减压蒸馏，收集120-130℃（0.53kPa）馏分，即得N-甲基二乙醇胺，收率为85%。2.由甲胺与环氧乙烷反应而得。温度保持在30℃以下，将环氧乙烷气体通入20%的甲胺溶液中进行加成反应，通至反应液的相对密度达到1.025为止。搅拌15min，相对密度不变即为终点。常压回收甲胺至103℃，减压蒸水后，收集119-170℃（4.67kPa）馏分。即为成品。收率72%。原料消耗定额：环氧乙烷950kg/t、甲胺（40%）870kg/t。此外，以甲醛与氰乙醇为原料，经催化加氢也可制得N-甲基二乙醇胺。
• 蒸气密度:4 (vs air)
• 防护措施:本品对大鼠，经口LD50为4.78mg/kg。